Expression of Cellular Oncogenes in Primary Cells from Human Leukemias
Alterations of cellular oncogene expression have been reported in numerous neoplasias, particularly of the hematopoietic system. However, a cause-effect relationship between cellular oncogene abnormalities and oncogenesis is still unclear. In order to explore the involvement of cellular oncogenes in human cancer cells, we studied the levels of the expression of three cellular protooncogenes in the primary leukemic cells from 53 leukemic patients with different types and stages.
KeywordsAcute Lymphoblastic Leukemia Chronic Lymphocytic Leukemia Chronic Lymphocytic Leukemia Patient Blast Crisis Oncogene Expression
Unable to display preview. Download preview PDF.
- 4.Chen SS, Cheng F, Rong GW et al. (1989) The molecular biological properties of a transplantable human primary gastric cancer in nude mice (THPGC-1). Chin J Oncol 11 (3): 171–174Google Scholar
- 5.Tang JQ, Chen SS (1988) Changes of expression and structure of some protoonco- genes in TPA induced HL-60 and Raji cells. Acta Biol Exp Sin 21: 201–208Google Scholar
- 8.Rossen D, Tereba A (1983) Transcription of hematopoietic associated oncogenes in childhood leukemias. Cancer Res 43: 3912–3916Google Scholar