Effect of Natural and Synthetic Peptides on the Biological Function of Leukemic Cells
The goal of this work was to study the influence of some naturally occurring peptides and their analogs on the impaired biological properties of blood cells derived from leukemic patients. The effect of human tuftsin and of the insect neuropetide, proctolin, and their synthetic derivatives on the phagocytosis of granulocytes and the influence of proctolin and its analogs on the blastic transformation of lymphocytes were investigated.
KeywordsAcute Lymphoblastic Leukemia Healthy Child Phagocytic Activity Leukemic Patient Blastic Transformation
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- 1.Kazanowska B, Bogusławska-Jaworska J, Konopińska D, Rodziewicz-Magott B (1988) The influence of proctolin and its analogs on the blastic transformation of ALL lymphocytes. Arch Immunol Ther Exp (Warsz) (in press).Google Scholar
- 2.Kazanowska B, Steuden W, Bogusławska-Jaworska B, Konopińska D (1987) The influence of synthetic tuftsin and its analogs on the function of granulocytes of children with ALL. Arch Immunol Ther Exp (Warsz) 35: 169Google Scholar
- 3.Konopińska D, Kazanowska B, Sobotka W, Bogusławska-Jaworska J (1986) An insect neuropeptide, proctolin. A new synthesis and its property of restoration of phagocytosis by defective human PMN leukocytes. Biull Pol Acad Sci 34: 327Google Scholar