The Effect of Human and Rat Fetal Bone on Hematopoiesis In Vitro and In Vivo

  • B. V. Afanasyev
  • V. A. Shatrov
  • N. Balayan
Conference paper
Part of the Haematology and Blood Transfusion / Hämatologie und Bluttransfusion book series (HAEMATOLOGY, volume 32)

Abstract

Granulocyte-macrophage colony-stimulating factor (GM-CSF) is a regulatory glycoprotein necessary for the proliferation, maturation, and survival of myeloid cells [4]. Myelopoiesis is enhanced when recombinant human (rh) GM-CSF is given to mice, monkeys [6], and some patients with various forms of neutropenia [3, 5]. The clinical use of rhGM-CSF infusions is under intensive investigation now.

Keywords

Agar DMSO Leukemia Neutropenia Cyclophosphamide 

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Copyright information

© Springer-Verlag Berlin Heidelberg 1989

Authors and Affiliations

  • B. V. Afanasyev
    • 1
  • V. A. Shatrov
    • 1
  • N. Balayan
    • 1
  1. 1.Department of Bone Marrow TransplantationN.N. Petrov Institute of OncologyLeningardUSSR

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