The Effect of Human and Rat Fetal Bone on Hematopoiesis In Vitro and In Vivo
Granulocyte-macrophage colony-stimulating factor (GM-CSF) is a regulatory glycoprotein necessary for the proliferation, maturation, and survival of myeloid cells . Myelopoiesis is enhanced when recombinant human (rh) GM-CSF is given to mice, monkeys , and some patients with various forms of neutropenia [3, 5]. The clinical use of rhGM-CSF infusions is under intensive investigation now.
KeywordsAgar DMSO Leukemia Neutropenia Cyclophosphamide
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