Leukotrienes in Airways and Blood Vessels

  • P. J. Piper
Conference paper
Part of the Bayer AG Centenary Symposium book series (BAYER)


Hydrolysis of phospholipids of the cell membrane by phospholipases gives rise to a wealth of extremely potent biologically active substances that may have important roles in human disease. One of the most recent outstanding biochemical and pharmacological achievements has been the elucidation of the metabolism of arachidonic acid and the discovery that it is the precursor of prostaglandins, prostacyclin, leukotrienes (LTs) and lipoxins. The possibility that there are yet more metabolites of this 20:4 fatty acid with high biological activity cannot be ruled out.


Allergy Clin Immunol Coronary Perfusion Pressure Coronary Constriction Parenchymal Strip Cardiac Anaphylaxis 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag Berlin Heidelberg 1989

Authors and Affiliations

  • P. J. Piper
    • 1
  1. 1.Department of Pharmacology, Hunterian InstituteRoyal College of SurgeonsLondonUK

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