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Hair and Hair Diseases pp 73–97Cite as

The Growing Anagen Hair

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Abstract

Although much of our present knowledge of the biophysics and biochemistry of hair stems from experimental research on animals [for review see also Orfanos et al. (1981)], recent data tell us that the physiological and biochemical properties of human hair are not identical with those of rodents or mammals phylogenetically older than man.

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References

  • Astbury WT, Woods HJ (1933) X-ray studies of the structure of hair, wool and related fibres. II. The molecular structure and elastic properties of hair keratin. Philos Trans Soc Lond (Series A) 232:333–394

    Article  Google Scholar 

  • Bern HA, Harkness DR, Blair SM (1955) Radioautographic studies of keratin formation. Proc Natl Acad Sci USA 41:55–60

    Article  PubMed  CAS  Google Scholar 

  • Birbeck MSC, Mercer EH (1957 a) The electron microscopy of the human hair follicle. I. Introduction and the hair cortex. J Biophys Biochem Cytol 3:202–214

    Google Scholar 

  • Birbeck MSC, Mercer EH (1957 b) The electron microscopy of the human hair follicle. II. The hair cuticle. J Biophys Biochem Cytol 3:215–222

    Article  PubMed  CAS  Google Scholar 

  • Birbeck MSC, Mercer EH (1957 c) The electron microscopy of the human hair follicle. III. The inner root sheath and trichohyaline. J Biophys Biochem Cytol 3:223–233

    Article  PubMed  CAS  Google Scholar 

  • Braun-Falco O (1958) The histochemistry of the hair follicle. In: Montagna W, Ellis RA (eds) The biology of hair growth. Academic, New York, pp 65–90

    Google Scholar 

  • Crewther WG, Fräser RDB, Lennox FG, Lindberg H (1965) The chemistry of keratins. Adv Protein Chem 20:191–346

    Article  PubMed  CAS  Google Scholar 

  • Dickerson RE, Geis I (1969) The structure and action of proteins. Harper and Row, New York

    Google Scholar 

  • Downes AM (1965) A study of the incorporation of labelled cystine into growing wool fibres. In: Lyne AG, Short ’BF (eds) Biology of skin and hair growth. Angus and Robertson, Sydney, Australia, pp 345–346

    Google Scholar 

  • Epstein WL, Maibach HI (1969) Cell proliferation and movement in human hair bulbs. In: Montagna W, Dobson RL (eds) Hair growth. Pergamon, Oxford, pp 83–97 (Advances in biology of skin, vol 9)

    Google Scholar 

  • Forslind B (1971a) Distribution of 35S-L-cystine in mice after intraperitoneal injection as revealed by whole-body autoradiography. Acta Derm Venereol (Stockh) 51:1–8

    CAS  Google Scholar 

  • Forslind B (1971 b) Electron microscopic and autoradiographic study of 35S-cystine incorporation in mouse hair follicles. Acta Derm Venereol (Stockh) 51:9–15

    CAS  Google Scholar 

  • Forslind B, Swanbeck G (1966) Keratin formation in the hair follicle. I. An ultrastructural investigation. Exp Cell Res 43:191–209

    Article  PubMed  CAS  Google Scholar 

  • Forslind B, Lindström B, Swanbeck G (1971) Microradiographic and autoradiographic studies of keratin formation in human hair. Acta Derm Venereol (Stockh) 51:81–88

    CAS  Google Scholar 

  • Forslind B, Afzelius BA, Liljesvan B, Roomans GM (1981) Green hairs: elementary X-ray analysis in the electron microscope. In: Orfanos CE, Montagna W, Stüttgen G (eds) Hair research. Springer, Berlin Heidelberg New York, pp 163–168

    Chapter  Google Scholar 

  • Forslind B, Li H-K, Malmqvist KR, Wiegleb D (1984) Elemental analysis of hair fibres using PIXE. A population study of sulfur content. Sci Total Environ

    Google Scholar 

  • Fraser RDB, MacRae TP (1982) The fine structure of keratin fibers. In: Breuer (ed) Milton Harris — chemist, innovator, and entrepreneur. American Chemical Society, pp 109–137

    Google Scholar 

  • Fraser RDB, MacRae TP, Rogers GE (1962) Molecular organization in a-keratin. Nature 193:1052–1055

    Article  PubMed  CAS  Google Scholar 

  • Fraser RDB, MacRae TP, Miller A (1964) Molecular structure of a-keratin. Nature 203:1231

    Article  CAS  Google Scholar 

  • Fraser RDB, MacRae TP, Millward GR, Parry DAD, Suzuki E, Tulloch PA (1971) The molecular structure of keratins. Appl Poly Symp 18:65–83

    Google Scholar 

  • Fraser RDB, MacRae TP, Suzuki E (1976) Structure of the a-keratin microfibril. J Mol Biol 108:435–452

    Article  CAS  Google Scholar 

  • Gillespie JM, Ries PJ, Schinckel PG (1964) The isolation and properties of some soluble proteins from wool. IX. The proteins in wools of increased sulphur content. Aust J Biol Sci 17:548–560

    CAS  Google Scholar 

  • Harkness DR, Bern HA (1957) Radioautographic studies of hair growth in mouse. Acta Anat (Basel) 31:35–45

    Article  CAS  Google Scholar 

  • Hashimoto K (1981) The environment of the hair follicle. In: Orfanos CE, Montagna W, Stüttgen G (eds) Hair research. Springer, Berlin Heidelberg New York, pp 172–182

    Chapter  Google Scholar 

  • Kassenbeck P (1981) Morphology and fine structure of hair. In: Orfanos CE, Montagna W, Stüttgen G (eds) Hair research. Springer, Berlin Heidelberg New York, pp 52–64

    Chapter  Google Scholar 

  • Lundgren HP, Ward WH (1962) Levels of molecular organization in a-keratins. Arch Biochem [Suppl] 1:78–111

    CAS  Google Scholar 

  • MacArthur I (1943) Structure of a-keratin. Nature 152:38–40

    Article  CAS  Google Scholar 

  • Mahrle G, Orfanos CE (1974) Das spongiöse Keratin und die Marksubstanz des menschlichen Kopfhaares. Raster- und Transmissionselektronenmikroskopische Untersuchungen. Arch Dermatol Forsch 241:305–316

    Article  Google Scholar 

  • Matoltsy AG, Parakkal PF (1965) Membrane coating granules of keratinizing epithelia. J Cell Biol 24:297–307

    Article  PubMed  CAS  Google Scholar 

  • Mercer EH (1965) The contribution of the resistant cell membranes to the properties of keratinized tissues. J Soc Cosmet Chem 16:507–514

    CAS  Google Scholar 

  • Monroe DD (1966) Hair growth measurements using intradermal sulphur-3 5-cystine. Arch Dermatol (Chicago) 93:119–122

    Google Scholar 

  • Montagna (1962) Structure and function of skin, 2nd edn. Academic, New York

    Google Scholar 

  • Orentreich N (1969) Scalp hair replacement in man. In: Montagna W, Dobson RL (eds) Hair growth. Pergamon, Oxford, pp 99–108 (Advances in biology of skin, vol 9)

    Google Scholar 

  • Orfanos CE, Ruska H (1968 a) Die Feinstruktur des menschlichen Haares. I. Die Haar-Cuticula. Arch Klin Exp Dermatol 231:97–110

    Article  PubMed  CAS  Google Scholar 

  • Orfanos CE, Ruska H (1968 b) Die Feinstruktur des menschlichen Haares. II. Der Haar-Cortex. Arch Klin Exp Dermatol 231:264–278

    Article  PubMed  CAS  Google Scholar 

  • Orfanos CE, Ruska H, Schade H (1971) Die histochemische Darstellung menschlicher Keratine mit Hilfe von saurem Natriumthioglycolat und Osmiumtetroxid. Arch Klin Exp Dermatol 240:404–418

    CAS  Google Scholar 

  • Orfanos CE, Montagna W, Stüttgen G (1981) Hair research. Status and future aspects. Springer, Heidelberg New York

    Google Scholar 

  • Orwin DFG (1979) The cytology and cytochemistry of the wool follicle. Int Rev Cytol 60:331–374

    Article  PubMed  CAS  Google Scholar 

  • Orwin DFG, Thomson RW (1973) Plasma membrane differentiations of keratinizing cells of the wool follicle. IV. Further membrane differentiations. J Ultrastruct Res 45:41–49

    Article  PubMed  CAS  Google Scholar 

  • Orwin DFG, Thomson RW, Flower NE (1973 a) Plasma membrane differentiation of keratinizing cells of the wool follicle. I. Gap junctions. J Ultrastruct Res 45:1–14

    Article  PubMed  CAS  Google Scholar 

  • Orwin DFG, Thompson RW, Flower NE (1973 b) Plasma membrane differentiation of keratinizing cells of the wool follicle. II. Desmosomes. J Ultrastruct Res 45:15–29

    Article  PubMed  CAS  Google Scholar 

  • Orwin OFG, Thompson RW, Flower NE (1973 c) Plasma membrane differentiation of keratinizing cells of the wool follicle. III. Tight junctions. J Ultrastruct Res 45:30–40

    Article  PubMed  CAS  Google Scholar 

  • Parakkal PF (1969) The fine structure of anagen hair follicle of the mouse. In: Montagna W, Dobson RL (eds) Hair growth. Pergamon, Oxford, pp 441–469 (Advances in biology of skin, vol 9)

    Google Scholar 

  • Parakkal PF, Matoltsy AG (1964) A study of the differentiation products of the hair follicle cells with the electron microscope. J Invest Dermatol 43:23–34

    Google Scholar 

  • Pauling L, Corey RB (1951) The structure of hair, muscle and related proteins. Proc Natl Acad Sci USA 37:261–271

    Article  PubMed  CAS  Google Scholar 

  • Rogers GE (1959) Electron microscopy of wool. J Ultrastruct Res 2:309–330

    Article  PubMed  CAS  Google Scholar 

  • Rogers GE (1963) The localization and significance of arginine and citrulline in proteins of the hair follicle. J Histochem Cytochem 11:700–705

    Article  CAS  Google Scholar 

  • Rogers GE (1964) Isolation and properties of inner sheath cells of hair follicles. Exp Cell Res 33:264–276

    Article  PubMed  CAS  Google Scholar 

  • Roth SI (1967) Hair and nail. In: Zelickson AS (ed) Ultrastructure of normal and abnormal skin. Lea and Febiger, Philadelphia, pp 105–131

    Google Scholar 

  • Steinert PM, Harding HWJ, Roger GE (1969) The characterization of protein bound citrulline. Biochim Biophys Acta 175:1–9

    PubMed  CAS  Google Scholar 

  • Steinert PM, Idler WW, Poirier MG, Katoh Y, Stoner GD, Yuspa SH (1979) Subunit structure of the mouse epidermal keratin filament. Biochim Biophys Acta 577:11–21

    PubMed  CAS  Google Scholar 

  • Suzuki E, Crewther WG, Fraser RDB, MacRae TP, McKern NM (1973) X-ray diffraction and infrared studies on an a-helical fragment from a-keratin. J Mol Biol 73:275–278

    Article  PubMed  CAS  Google Scholar 

  • Swanbeck G (1961) The structure of a-keratin. Exp Cell Res 23:420–422

    Article  PubMed  CAS  Google Scholar 

  • Swanbeck G (1964) A theory for the structure of a-keratin. In: Montagna W, Lobiz (eds) The epidermis. Academic, New York, pp 339–350

    Google Scholar 

  • Swift JA (1968) The electron histochemistry of cystine-containing proteins in thin transverse sections of human hair. J R Microsc Soc 88:449–160

    Article  PubMed  CAS  Google Scholar 

  • Swift JA (1981) The hair surface. In: Orfanos CE, Montagna W, Stüttgen G (eds) Hair research. Springer, Berlin Heidelberg New York, pp 65–72

    Chapter  Google Scholar 

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Authors
  1. B. Forslind
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Editors and Affiliations

  1. Department of Dermatology, University Medical Center Steglitz, The Free University of Berlin, Berlin, FR Germany

    Constantin E. Orfanos

  2. Department of Dermatology, University of Nijmegen, NL-6500 HB, Nijmegen, The Netherlands

    Rudolf Happle

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© 1990 Springer-Verlag Berlin Heidelberg

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Forslind, B. (1990). The Growing Anagen Hair. In: Orfanos, C.E., Happle, R. (eds) Hair and Hair Diseases. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-74612-3_4

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  • DOI: https://doi.org/10.1007/978-3-642-74612-3_4

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-74614-7

  • Online ISBN: 978-3-642-74612-3

  • eBook Packages: Springer Book Archive

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