Epidemiologic Studies of Populations Exposed to Motor Vehicle Exhausts and Polycyclic Aromatic Hydrocarbons
Many epidemiologic studies over the last 3 decades have confirmed the association of workplace exposure to polycyclic aromatic hydrocarbons (PAHs) and lung cancer (Lindstedt and Sollenberg 1982). However, most of these studies were of workers with very high exposure from nonmotor vehicle sources (e.g., gas retort and coke oven workers) (Lawther et al. 1965; Lloyd 1971). In addition, exposures in these occupations may also have been qualitatively different from motor vehicle exhausts. More recent epidemiologic studies have focused on workplace exposure to motor vehicle exhaust, with the greatest amount of such work on populations exposed to diesel exhaust. These epidemiologic studies have provided useful data on human risks of lung cancer associated with exposure to diesel exhaust, but have not been useful in evaluating lung cancer risk from gasoline engine exhaust. Population-based studies are limited in their ability to evaluate causal associations of air pollution or PAHs with specific health outcomes, and do not provide useful data for assessing the lung cancer risks associated with motor vehicle exhausts.
KeywordsEnvironmental Tobacco Smoke Diesel Exhaust Lung Cancer Risk Environmental Tobacco Smoke Exposure Engine Exhaust
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