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Untersuchungen zur traumainduzierten Monokinsynthese — Erster klinischer Nachweis des Neutrophil Activating Factor (NAF)

Study of Trauma-Induced Monokine Synthesis — First Clinical Demonstration of Neutrophil Activating Factor

  • Conference paper
Book cover 106. Kongreß der Deutschen Gesellschaft für Chirurgie München, 29. März — 1. April 1989

Part of the book series: Deutsche Gesellschaft für Chirurgie ((FORUMBAND,volume 89))

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Zusammenfassung

Intakte Monocyten-(Mo) Funktion ist eine conditio sine qua non für den ungestörten Ablauf zellvermittelter Immunmechanismen (CMI). Aus der Reihe der bisher charakterisierten Mo-Dysfunktionen nach Trauma sind vor allem verminderte Kapazität der Antigenpräsentation und alterierte Monokinsyntheseverhalten zu nennen (1, 3, 4, 7). Insbesondere das von uns nach schwerer Mehrfachverletzung gezeigte Shifting der Monokinausschüttung mit hoher Syntheserate des suppressorisch immunreaktiven PGE2 zuungunsten der IL-1-Synthese ist ein essentielles Charakteristicum verminderter CMI (2).

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Literatur

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Author information

Authors and Affiliations

  1. Klinikum Großhadern, Chirurgische Klinik und Poliklinik, Marchioninistr. 15, D-8000, München 70, Deutschland

    M. Storck

  2. Chirurgische Klinik und Poliklinik, LMU München, Klinikum Großhadern, Deutschland

    M. Storck, E. Faist, W. Ertel & G. Heberer

  3. Theodor-Kocher-Institut, Universität Bern, Deutschland

    A. Walz & M. Baggiolini

Authors
  1. M. Storck
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  2. E. Faist
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  3. W. Ertel
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  4. A. Walz
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  5. M. Baggiolini
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  6. G. Heberer
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Editor information

Editors and Affiliations

  1. Chirurgische Universitätsklinik, Im Neuenheimer Feld 100, D-6900, Heidelberg, Deutschland

    Christian Herfarth

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© 1989 Springer-Verlag Berlin Heidelberg

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Storck, M., Faist, E., Ertel, W., Walz, A., Baggiolini, M., Heberer, G. (1989). Untersuchungen zur traumainduzierten Monokinsynthese — Erster klinischer Nachweis des Neutrophil Activating Factor (NAF). In: Herfarth, C. (eds) 106. Kongreß der Deutschen Gesellschaft für Chirurgie München, 29. März — 1. April 1989. Deutsche Gesellschaft für Chirurgie, vol 89. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-74573-7_16

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  • DOI: https://doi.org/10.1007/978-3-642-74573-7_16

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-50898-4

  • Online ISBN: 978-3-642-74573-7

  • eBook Packages: Springer Book Archive

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