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Oral Immunization for the Prevention of Dental Diseases

  • Conference paper
New Strategies for Oral Immunization

Part of the book series: Current Topics in Microbiology and Immunology ((CT MICROBIOLOGY,volume 146))

Abstract

Interference with dental caries using immunological stratagems are generally based on three assumptions. The first assumption is that the disease is infectious in nature. The second assumption is that some process in the colonization, growth or pathogenesis of the putative cariogenic bacterium is vulnerable to immunological attack. The third assumption is that products of specific host defense networks can be marshalled at these vulnerable sites for a sufficient time period to interfere with the eventual demineralization of the tooth enamel. We shall discuss the evidence for these assumptions and specifically explore the past experience with, and future potential for immunity induced by the oral route of immunization.

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Author information

Authors and Affiliations

  1. Department of Immunology, Forsyth Dental Center, 140 Fenway, Boston, MA, 02115, USA

    M. A. Taubman & D. J. Smith

Authors
  1. M. A. Taubman
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  2. D. J. Smith
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Editor information

Editors and Affiliations

  1. Medicine and Oral Biology, USA

    Jiri Mestecky M.D. (Professor of Microbiology) (Professor of Microbiology)

  2. Department of Microbiology, University of Alabama at Birmingham, UAB Station, 35 294, Birmingham, Alabama, USA

    Jerry R. McGhee Ph. D. (Professor of Microbiology) (Professor of Microbiology)

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© 1989 Springer-Verlag Berlin · Heidelberg

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Taubman, M.A., Smith, D.J. (1989). Oral Immunization for the Prevention of Dental Diseases. In: Mestecky, J., McGhee, J.R. (eds) New Strategies for Oral Immunization. Current Topics in Microbiology and Immunology, vol 146. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-74529-4_20

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  • DOI: https://doi.org/10.1007/978-3-642-74529-4_20

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-74531-7

  • Online ISBN: 978-3-642-74529-4

  • eBook Packages: Springer Book Archive

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