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Immunity to Rotaviruses

  • Conference paper
New Strategies for Oral Immunization

Part of the book series: Current Topics in Microbiology and Immunology ((CT MICROBIOLOGY,volume 146))

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Abstract

Diarrhea is the principal cause of mortality in infants and young children in the developing countries of Asia, Africa, and Latin America where the syndrome accounts annually for 3–5 billion cases and approximately 5–10 million deaths (Institute of Medicine 1985; Walsh and Warren 1979). Another estimate which reviewed data from several longitudinal studies in children revealed that 4.6 million diarrhea deaths and 744 million to 1 billion episodes of diarrhea occurred in children less than 5 years of age in developing countries, excluding China (Snyder and Merson 1982). In developed countries diarrheal deaths occur infrequently but morbidity from diarrheal illness is high (Institute of Medicine 1986; Rodriguez et al. 1987).

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Author information

Authors and Affiliations

  1. Clinical and Epidemiological Studies Branch, Microbiology and Infectious Diseases Program, Bethesda, MD, 20892, USA

    R. Edelman

  2. Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD, 20892, USA

    J. Flores & A. Z. Kapikian

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  1. R. Edelman
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  2. J. Flores
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Editors and Affiliations

  1. Medicine and Oral Biology, USA

    Jiri Mestecky M.D. (Professor of Microbiology) (Professor of Microbiology)

  2. Department of Microbiology, University of Alabama at Birmingham, UAB Station, 35 294, Birmingham, Alabama, USA

    Jerry R. McGhee Ph. D. (Professor of Microbiology) (Professor of Microbiology)

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© 1989 Springer-Verlag Berlin · Heidelberg

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Edelman, R., Flores, J., Kapikian, A.Z. (1989). Immunity to Rotaviruses. In: Mestecky, J., McGhee, J.R. (eds) New Strategies for Oral Immunization. Current Topics in Microbiology and Immunology, vol 146. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-74529-4_14

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  • DOI: https://doi.org/10.1007/978-3-642-74529-4_14

  • Publisher Name: Springer, Berlin, Heidelberg

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