Abstract
In tight epithelia, such as the toad urinary bladder and the mammalian collecting duct, a brisk transepithelial water flow can be induced by establishing a transepithelial osmotic gradient in the presence of antidiuretic hormone (ADH). Typically, water flow is accompanied by extensive cellular swelling (Peachey and Rasmussen, 1961; Ganote et al., 1968; Kirk et al., 1984) which, unlike swelling which is not caused by transcellular water flow, is largely confined to the apical pole of the epithelial cell while the basal pole is only marginally distended (DiBona et al., 1969). Based on this finding, DiBona (1981) proposed that cytoplasmic water flow induces an intracellular standing gradient of solutes and, therefore, gradient of water activity.
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References
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© 1989 Springer-Verlag Berlin Heidelberg
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Rick, R., Schratt, W. (1989). Distribution of Ions and Water in Epithelial Cells and Tissues. In: Zierold, K., Hagler, H.K. (eds) Electron Probe Microanalysis. Springer Series in Biophysics, vol 4. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-74477-8_16
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DOI: https://doi.org/10.1007/978-3-642-74477-8_16
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