Abstract
A systematic discussion of biological electron-probe microanalysis would examine one-by-one several aspects of the subject, including (at least) specimen preparation, specimen imaging, analytical spatial resolution, concentration limits for elemental detection, beam damage, methods of quantitative analysis and a review of the categories of biological studies and of the notable biological results (for example, see Hall, 1979.) Instead, here we shall try to trace the actual path of development of the method, a development shaped of course by the interaction of all of these aspects as the available instrumentation became ever more effective.
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Hall, T.A. (1989). The History of Electron Probe Microanalysis in Biology. In: Zierold, K., Hagler, H.K. (eds) Electron Probe Microanalysis. Springer Series in Biophysics, vol 4. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-74477-8_1
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