Efficacy of Systemic Chemotherapy in Metastatic Murine Bladder Cancer

  • W. Kropp
  • M.-L. Mlynek
  • G. Cevc
  • R. Hartung
Conference paper

Abstract

So far, the efficiency of chemotherapy has been tested on FANFT-induced tumors of the bladder in mice and in rats, as well as on transplanted carcinoma of the bladder in immunocompetent mice and nude mice (Huland et al. 1985; Soloway 1977; Solo-way and Masters 1980). Animal models for the study of cancer metastasis have been developed for a number of tumors and have been used for the study of the mechanisms of metastasis (Nicolson 1982).

Keywords

Toxicity Cage Polyethylene Trypsin Methotrexate 

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References

  1. Huland H, Otto U, Paleske AV (1985) Chemotherapy and human bladder carcinoma transplanted into NMRI NU/NU mice. J Urol 184: 601Google Scholar
  2. Nicolson G (1982) Cancer metastasis. Organ colonization and the cell-surface properties of malignant cells. Biochim Biophys Acta 695: 113PubMedGoogle Scholar
  3. Soloway MS (1977) Intravesical and systemic chemotherapy of murine bladder cancer. Cancer Res 37: 2918PubMedGoogle Scholar
  4. Soloway MS, Masters S (1980) Urothelial susceptibility to tumor cell implantation. Cancer 46: 1158PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1989

Authors and Affiliations

  • W. Kropp
  • M.-L. Mlynek
  • G. Cevc
  • R. Hartung
    • 1
  1. 1.Klinikum Rechts der IsarUrologische Klinik und Poliklinik der Technischen Universität MünchenMünchen 80Germany

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