Clinical Implications of the Pharmacokinetics of Tricyclic Antidepressants

  • J. C. Nelson
  • C. Mazure
  • P. I. Jatlow
Part of the Psychopharmacology Series book series (PSYCHOPHARM, volume 7)

Abstract

Knowledge gained during the past 20 years about the pharmacokinetics of tricyclic antidepressant drugs has helped to refine clinical practice. This discussion will focus on kinetic features of tricyclic antidepressants which appear to have important implications for clinical practice.

Keywords

Placebo Toxicity Depression Noradrenaline Tricyclic 

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Copyright information

© Springer-Verlag Berlin Heidelberg 1989

Authors and Affiliations

  • J. C. Nelson
  • C. Mazure
  • P. I. Jatlow
    • 1
    • 2
  1. 1.Department of PsychiatryYale University School of MedicineNew HavenUSA
  2. 2.Yale-New Haven HospitalYale University School of MedicineNew HavenUSA

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