Selenium in Children with Acute Leukaemia During Selenium Chemotherapy

  • D. Frosch
  • S. Knab
  • H. Jürgens
  • H. Menzel
  • I. Lombeck
Conference paper

Abstract

In animals selenium was reported to show an inhibitory effect on carcinogenesis and to reduce the growth rate of tumors (Shamberger 1979). Epidemiological studies led to the hypothesis of an inverse correlation between average daily selenium intake and human cancer mortality in some countries (Clark 1985; Burk 1986).

Keywords

Glutathione Selenium Hydride Thrombocytopenia Spectrophotometry 

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References

  1. Burk RF (1986) Selenium and cancer; meaning of serum selenium levels. J Nutr 116: 1584–1586PubMedGoogle Scholar
  2. Clark LC (1985) The epidemiology of selenium and cancer. Fed Proc 44: 2584–2589PubMedGoogle Scholar
  3. Shamberger RJ (1979) Relationship of selenium to cancer. I. Inhibitory effect of selenium on carcinogenesis. J Am Cancer Inst 44: 931–936Google Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1989

Authors and Affiliations

  • D. Frosch
    • 1
  • S. Knab
    • 1
  • H. Jürgens
    • 1
  • H. Menzel
    • 2
  • I. Lombeck
    • 1
  1. 1.Kinderklinik IUniversitätsklinik DüsseldorfDüsseldorfGermany
  2. 2.Institut für ToxikologieUniversität DüsseldorfDüsseldorfGermany

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