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Altered Regulation of Receptor-Associated Tyrosine Kinases in Human Tumors

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Molecular Basis of Membrane-Associated Diseases

Abstract

The discovery of a link between known oncogenes and growth factors, their receptors and their signalling mechanisms has renewed hopes that the basic features of cancerous growth can be understood. Such an understanding could provide novel means of diagnosing and treating cancer. It is now established that several of the so-called activated oncogenes are altered versions of genes encoding proteins involved in the intercellular and intracellular signalling pathways (for reviews, see Bishop 1983; Hunter 1984; James and Bradshow 1984; Ben-Neriah and Baltimore 1986).

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Authors and Affiliations

  1. University of Torino, Medical School, Torino, 10126, Italy

    P. M. Comoglio, M. F. Direnzo, G. Gaudino, S. Giordano, L. Naldini & C. Ponzetto

  2. Dept. Biomedical Sciences, C. so M. D’Azeglio 52, 10126, Torino, Italy

    P. M. Comoglio

Authors
  1. P. M. Comoglio
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  2. M. F. Direnzo
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  3. G. Gaudino
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  4. S. Giordano
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  5. L. Naldini
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  6. C. Ponzetto
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Editor information

Editors and Affiliations

  1. Institut für Biochemie und Molekularbiologie, Universität Bern, Bühlstraße 28, CH-3012, Bern, Switzerland

    Angelo Azzi

  2. Institute of Physiology, Czechoslovak Academy of Sciences, Videnska 1083, CS-142 20, Praha 4, Czech Republic

    Zdenek Drahota

  3. Institute of Medical Biochemistry and Chemistry, University of Bari, Piazza G. Cesare, I-70124, Bari, Italy

    Sergio Papa

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© 1989 Springer-Verlag Berlin Heidelberg

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Comoglio, P.M., Direnzo, M.F., Gaudino, G., Giordano, S., Naldini, L., Ponzetto, C. (1989). Altered Regulation of Receptor-Associated Tyrosine Kinases in Human Tumors. In: Azzi, A., Drahota, Z., Papa, S. (eds) Molecular Basis of Membrane-Associated Diseases. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-74415-0_5

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  • DOI: https://doi.org/10.1007/978-3-642-74415-0_5

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-74417-4

  • Online ISBN: 978-3-642-74415-0

  • eBook Packages: Springer Book Archive

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