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Transmembrane Ionic Fluxes in the Brain in Energy-Depleted Cells

  • B. K. Siesjö
Conference paper

Abstract

The membranes of brain cells, particularly neurons, have a high resting permeability to ions. This “leakiness” is reflected in the high consumption of energy which, to a very large extent, seems to be utilized to pump ions against constant leak fluxes along dissipative pathways. Thus, when energy production is arrested, as occurs in anoxia or in hypoglycemic coma, ion gradients in the brain are quickly dissipated.

Keywords

Mean Arterial Blood Pressure Excitatory Amino Acid Cortical Spreading Depression Spreading Depression Energy Failure 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Berlin Heidelberg 1989

Authors and Affiliations

  • B. K. Siesjö
    • 1
  1. 1.Laboratory for Experimental Brain ResearchUniversity of LundSweden

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