Skip to main content

Recent Advances in Combined Heart-Lung Transplantation

  • Conference paper
Assisted Circulation 3
  • 75 Accesses

Abstract

Heart-lung transplantation has been successfully applied in the treatment of combined end-stage cardiopulmonary disease for approximately 6 years. Estimates on the number of patients who have undergone heart-lung transplantation during this period range from 100 to 200 persons worldwide, with the most frequent indications for transplantation consisting of primary pulmonary hypertension and end-stage Eisenmenger’s complex. The procedure has been successfully performed in both pediatric and adult patients. In the authors’ experience, approximately 70% 1-year survival can be expected, with excellent prospects for normal long-term cardiopulmonary function in most patients.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 39.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Haglin J, Telander RL, Muzzaal RE, Kiser JC, Strobel CJ (1963) Comparison of lung autotransplantation in the primate and dog. Surg Forum 14:196

    PubMed  CAS  Google Scholar 

  2. Cooley DA, Bordwell RD, Hallman GL (1969) Organ transplantation for advanced cardiopulmonary disease. Ann Thorac Surg 8:30

    Article  PubMed  CAS  Google Scholar 

  3. Wildervuur CR, Benfied JR (1970) A review of 23 human lung transplants by 20 surgeons. Ann Thorac Surg 9:489

    Article  Google Scholar 

  4. Reitz BA, Burton NA, Jamieson SW, Bieber CP, Pennock JL, Stinson EB, Shumway NE (1980) Heart and lung transplantation: autotransplantation and allotransplantation in primates with extended survival. J Thorac Cardiovasc Surg 80:360

    PubMed  CAS  Google Scholar 

  5. Jamieson SW, Stinson EB, Oyer PE, Baldwin JC, Shumway NE (1984) Operative technique for heart-lung transplantation. J Thorac Cardiovasc Surg 87:930

    PubMed  CAS  Google Scholar 

  6. Jamieson SW (1986) Heart-lung transplantation. In: Jamieson SW, Shumway NE (eds) Rob and Smith’s operative surgery. Mosby, St Louis, pp 594–605

    Google Scholar 

  7. McGregor CG, Baldwin JC, Jamieson SW (1985) Isolated pulmonary rejection after combined heart and lung transplantation. Thorac Cardiovasc Surg 90:623

    CAS  Google Scholar 

  8. Reitz BA, Gaudiani VA, Hunt SA, Wallwork J, Billingham ME, Oyer PE, Baumgartner WA, Jamieson SW, Stinson EB, Shumway NE (1983) Diagnosis and treatment of allograft rejection in heart-lung transplant patients. J Thorac Cardiovasc Surg 85:354

    PubMed  CAS  Google Scholar 

  9. Burke CM, Theodore J, Dawkins KD, Yousem SA, Blank N, Billingham ME, VanKessel A, Jamieson SW, Baldwin JC, Oyer PE, Stinson EB, Shumway NE, Robin ED (1984) Posttransplant obliterative bronchiolitis and other late lung sequelae in human heart-lung transplantation. Chest 86:824

    Article  PubMed  CAS  Google Scholar 

  10. Dawkins KD, Jamieson SW, Hunt SA, Baldwin JC, Burke CM, Morris A, Billingham ME, Theodore J, Oyer PE, Stinson EB, Shumway NE (1985) Long-term results, hemodynamics, and complications after combined heart-lung transplantation. Circulation 71:919

    Article  PubMed  CAS  Google Scholar 

  11. Myers BD, Ross J, Newton L, Leutscher J, Perlroth M (1984) Cyclosporine A associated chronic nephropathy in potentially irreversible renal injury. N Engl J Med 311:699

    Article  PubMed  CAS  Google Scholar 

  12. Burke CM, Baldwin JC, Morris AJ, Shumway NE, Theodore J, Tazelaar HD, McGregor C, Robin ED, Jamieson SW (1986) Twenty-eight cases of human heart-lung transplants. Lancet:517

    Google Scholar 

  13. Prop J, Wildevuur CR, Nieuwenhuis P (1985) Lung allograft rejection after combined heart and lung transplantation. J Thorac Cardiovasc Surg 90:623

    Google Scholar 

  14. Ladowski JS, Kapelanski DD, Teodori MF, Stevenson WC, Hardesty RL, Griffith BP (1985) Experimental use of an autoperfusing heart-lung bloc for organ preservation prior to heart-lung transplantation. Heart Transplant 4(2): 128

    Google Scholar 

  15. Starkey TD, Sakakibara N, Hagberg RC, Baldwin JC, Jamieson SW (1985) Successful six hour cardiopulmonary preservation with simple hypothermic crystalloid flush. Heart Transplant 4(6): 601

    Google Scholar 

Download references

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1989 Springer-Verlag Berlin Heidelberg

About this paper

Cite this paper

Tuna, I.C., Jamieson, S.W. (1989). Recent Advances in Combined Heart-Lung Transplantation. In: Unger, F. (eds) Assisted Circulation 3. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-74404-4_39

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-74404-4_39

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-74406-8

  • Online ISBN: 978-3-642-74404-4

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics