Abstract
Heart-lung transplantation has been successfully applied in the treatment of combined end-stage cardiopulmonary disease for approximately 6 years. Estimates on the number of patients who have undergone heart-lung transplantation during this period range from 100 to 200 persons worldwide, with the most frequent indications for transplantation consisting of primary pulmonary hypertension and end-stage Eisenmenger’s complex. The procedure has been successfully performed in both pediatric and adult patients. In the authors’ experience, approximately 70% 1-year survival can be expected, with excellent prospects for normal long-term cardiopulmonary function in most patients.
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Haglin J, Telander RL, Muzzaal RE, Kiser JC, Strobel CJ (1963) Comparison of lung autotransplantation in the primate and dog. Surg Forum 14:196
Cooley DA, Bordwell RD, Hallman GL (1969) Organ transplantation for advanced cardiopulmonary disease. Ann Thorac Surg 8:30
Wildervuur CR, Benfied JR (1970) A review of 23 human lung transplants by 20 surgeons. Ann Thorac Surg 9:489
Reitz BA, Burton NA, Jamieson SW, Bieber CP, Pennock JL, Stinson EB, Shumway NE (1980) Heart and lung transplantation: autotransplantation and allotransplantation in primates with extended survival. J Thorac Cardiovasc Surg 80:360
Jamieson SW, Stinson EB, Oyer PE, Baldwin JC, Shumway NE (1984) Operative technique for heart-lung transplantation. J Thorac Cardiovasc Surg 87:930
Jamieson SW (1986) Heart-lung transplantation. In: Jamieson SW, Shumway NE (eds) Rob and Smith’s operative surgery. Mosby, St Louis, pp 594–605
McGregor CG, Baldwin JC, Jamieson SW (1985) Isolated pulmonary rejection after combined heart and lung transplantation. Thorac Cardiovasc Surg 90:623
Reitz BA, Gaudiani VA, Hunt SA, Wallwork J, Billingham ME, Oyer PE, Baumgartner WA, Jamieson SW, Stinson EB, Shumway NE (1983) Diagnosis and treatment of allograft rejection in heart-lung transplant patients. J Thorac Cardiovasc Surg 85:354
Burke CM, Theodore J, Dawkins KD, Yousem SA, Blank N, Billingham ME, VanKessel A, Jamieson SW, Baldwin JC, Oyer PE, Stinson EB, Shumway NE, Robin ED (1984) Posttransplant obliterative bronchiolitis and other late lung sequelae in human heart-lung transplantation. Chest 86:824
Dawkins KD, Jamieson SW, Hunt SA, Baldwin JC, Burke CM, Morris A, Billingham ME, Theodore J, Oyer PE, Stinson EB, Shumway NE (1985) Long-term results, hemodynamics, and complications after combined heart-lung transplantation. Circulation 71:919
Myers BD, Ross J, Newton L, Leutscher J, Perlroth M (1984) Cyclosporine A associated chronic nephropathy in potentially irreversible renal injury. N Engl J Med 311:699
Burke CM, Baldwin JC, Morris AJ, Shumway NE, Theodore J, Tazelaar HD, McGregor C, Robin ED, Jamieson SW (1986) Twenty-eight cases of human heart-lung transplants. Lancet:517
Prop J, Wildevuur CR, Nieuwenhuis P (1985) Lung allograft rejection after combined heart and lung transplantation. J Thorac Cardiovasc Surg 90:623
Ladowski JS, Kapelanski DD, Teodori MF, Stevenson WC, Hardesty RL, Griffith BP (1985) Experimental use of an autoperfusing heart-lung bloc for organ preservation prior to heart-lung transplantation. Heart Transplant 4(2): 128
Starkey TD, Sakakibara N, Hagberg RC, Baldwin JC, Jamieson SW (1985) Successful six hour cardiopulmonary preservation with simple hypothermic crystalloid flush. Heart Transplant 4(6): 601
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© 1989 Springer-Verlag Berlin Heidelberg
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Tuna, I.C., Jamieson, S.W. (1989). Recent Advances in Combined Heart-Lung Transplantation. In: Unger, F. (eds) Assisted Circulation 3. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-74404-4_39
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DOI: https://doi.org/10.1007/978-3-642-74404-4_39
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-74406-8
Online ISBN: 978-3-642-74404-4
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