Abstract
The human implantation of the first total artificial heart (TAH) in 1969 by Cooley [1, 2] represented the efforts of many investigators and many years of research. During this and other implants to follow, the TAH clearly demonstrated its capacity to anatomically and functionally replace the diseased natural heart, relieving heart failure and restoring cardiac hemodynamics to normal. Further laboratory investigation was stimulated by these results and has since led to the development of more advanced device designs which incorporate advances in biocompatibility and mechanical reliability of the components and driving systems. Select clinical applications of the currently available devices have shown promising results, generating an increasing interest in more widespread clinical application of TAH devices [3–8].
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Cooley DA, Liotta D, Hallman GL (1969) Orthotopic cardiac prosthesis for two-staged cardiac replacement. Am J Cardiol 24:723–730
Cooley DA, Liotta D, Hallman GL, Bloodwell RD, Leachman RD, Milan JD (1969) First human implantation of cardiac prosthesis for staged total replacement of the heart. Trans Am Soc Artif Intern Organs 15:252–263
DeVries WC, Anderson JL, Joyce LD, Anderson FL, Hammond E, Jarvik RK, Kolff WJ (1984) Clinical use of the total artificial heart. N Engl J Med 310(5):273–278
Copeland JG, Emery RW, Levinson NM, Copeland J, McAleer MJ, Riley JE (1985) The role of mechanical support and transplantation in treatment of patients with end-stage cardiomyopathy. Circulation 70(2):7–12
Levinson M, Smith R, Cole R, Gallo J, Icenogle TB, Emery R, Ott R, Copeland J (1986) Three recent cases of the total artificial heart before transplantation. J Heart Transplant 5:215–228
Copeland JG, Levinson NM, Vaughn C, Cheng K, Icenagle TB, Austen J, Riley JE (1986) The total artificial heart as a bridge to transplantation. JAMA 256(21):2991–2995
Griffith BP, Kormos R, Wei LM, Borovetz HS, Trento A, Hardesty RL (1986) Use of the total artificial heart as an interim device: initial experience in Pittsburgh with four patients. J Heart Transplant 5(3):210–214
Griffith BP, Hardesty RL, Kormos R, Trento A, Borovetz HS, Thompson M, Bahnsen H (1987) Temporary use of the Jarvik-7 total artificial heart before transplantation. N Engl J Med 316:130–134
Olsen DB, Riebman JB, DePaulis R, Durrant G, Nielsen SD (1987) Registry and tabulations of orthotopic total artificial hearts in man. Trans Am Soc Artif Intern Organs 33(3):182–191
DePaulis R, Riebman JB, Deleuze P, Olsen DB (1987) The total artificial heart: indications and preliminary results. J Cardiac Surg 1987 (in press)
Joyce LD, Johnson KE, Pierce WS et al. (1986) Summary of the world experience with clinical use of total artificial hearts as heart support devices. J Heart Transplant 5:229–235
Levinson MM, Smith RG, Cork RC, Gallo J, Emery RW, Icenagle TB, Ott RA, Burns GL, Copeland JG (1986) Thromboembolic complications of the Jarvik-7 total artificial heart: case report. Artif Organs 10(3):236–244
Wurzel D, Kolff J, Missfeldt W, Wildevuur W, Hansen G, Brownstein L, Riebman J, DePaulis R, Kolff WJ (1987) Development of the Philadelphia heart system. ESAO 14: (in press)
Wurzel D, Wildevur W, Kolff J (1986) Instrumentation for deriving pneumatic TAH control signals from the drivelines pressure and flow. Trans Am Soc Artif Intern Organs 32:258–262
Wurzel D (1986) Cardiac prosthesis having integral blood pressure sensor. US Patent Application no 857896
Missfeldt W, Wurzel D, Kolff J (1986) An air powered artificial heart all pneumatic Driver. ABST internal symposium on artificial organs. Biomed Eng Transplant
Kolff J, Cavarocchi NC, Riebman JB, Jessup M (1988) The artificial heart; design capabilities and indications in the treatment of heart failure. Heart Failure (in press)
Farrar DJ, Hill JD, Gray LA, Pennington DG, McBride LR, Pierce WS, Pae WE, Glenville B, Ross D, Galbraith TA, Zambro GL (1988) Heterotopic prosthetic ventricles as a bridge to cardiac transplantation, a multicenter study in 29 patients. N Engl J Med 318:335–340
Inou N (1984) Quantitative approach to determine the application time of the left ventricular assist device. Artif Organ 8:458
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1989 Springer-Verlag Berlin Heidelberg
About this paper
Cite this paper
Kolff, J., Wurzel, P., Riebman, J.B. (1989). The Philadelphia Heart System — An Implantable Artificial Heart for a Transplant Center. In: Unger, F. (eds) Assisted Circulation 3. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-74404-4_27
Download citation
DOI: https://doi.org/10.1007/978-3-642-74404-4_27
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-74406-8
Online ISBN: 978-3-642-74404-4
eBook Packages: Springer Book Archive