The Philadelphia Heart System — An Implantable Artificial Heart for a Transplant Center

  • J. Kolff
  • P. Wurzel
  • J. B. Riebman
Conference paper


The human implantation of the first total artificial heart (TAH) in 1969 by Cooley [1, 2] represented the efforts of many investigators and many years of research. During this and other implants to follow, the TAH clearly demonstrated its capacity to anatomically and functionally replace the diseased natural heart, relieving heart failure and restoring cardiac hemodynamics to normal. Further laboratory investigation was stimulated by these results and has since led to the development of more advanced device designs which incorporate advances in biocompatibility and mechanical reliability of the components and driving systems. Select clinical applications of the currently available devices have shown promising results, generating an increasing interest in more widespread clinical application of TAH devices [3–8].


Artificial Heart Mechanical Circulatory Support Total Artificial Heart Blood Chamber Human Implantation 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag Berlin Heidelberg 1989

Authors and Affiliations

  • J. Kolff
  • P. Wurzel
  • J. B. Riebman

There are no affiliations available

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