The Philadelphia Heart System — An Implantable Artificial Heart for a Transplant Center
The human implantation of the first total artificial heart (TAH) in 1969 by Cooley [1, 2] represented the efforts of many investigators and many years of research. During this and other implants to follow, the TAH clearly demonstrated its capacity to anatomically and functionally replace the diseased natural heart, relieving heart failure and restoring cardiac hemodynamics to normal. Further laboratory investigation was stimulated by these results and has since led to the development of more advanced device designs which incorporate advances in biocompatibility and mechanical reliability of the components and driving systems. Select clinical applications of the currently available devices have shown promising results, generating an increasing interest in more widespread clinical application of TAH devices [3–8].
KeywordsGraphite Ischemia Coumadin Expense Cardiomyopathy
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