Abstract
With the introduction of the potent and more selective immunosuppressant cyclosporin A (CsA) in the early 1980s [1–3], cardiac transplantation changed from an experimental procedure into an accepted therapeutic modality. Since that time, transplantation has offered the only hope for numerous patients with end-stage heart disease. Donor availability has not kept pace with the growing number of patients awaiting cardiac transplantation, however, and approximately 20% of potential transplant recipients die before a suitable donor can be found [4]. This dilemma has led to a renewed interest in “staged” cardiac replacement, using mechanical circulatory support to sustain these patients during the critical waiting period.
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References
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© 1989 Springer-Verlag Berlin Heidelberg
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Frazier, O.H., Cooley, D.A. (1989). Use of Cardiac Assist Devices as Bridges to Cardiac Transplantation: Review of Current Status and Report of the Texas Heart Institute’s Experience. In: Unger, F. (eds) Assisted Circulation 3. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-74404-4_22
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DOI: https://doi.org/10.1007/978-3-642-74404-4_22
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