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Sodium Cromoglycate in the Management of Food Allergy in Children

  • L. Businco
  • A. Cantani
  • P. Meglio
  • P. G. Giampietro
Conference paper

Abstract

Children with disorders related to adverse reactions to foods are frequently a puzzle for allergists as regards both diagnosis and therapy. It is assumed that food allergens stimulate mediator release from the superficial mast cells located in the gut, thereby inducing an increased permeability of the gastrointestinal (GI) tract. Food protein absorption into the blood stream ensues, which is followed by atopic manifestations at distant sites, such as angioedema, atopic dermatitis (AD), urticaria, asthma, and GI symptoms, the latter being provoked by the effects on the gut itself. It has been shown by experimental models that local anaphylaxis is associated with increased GI porosity to the antigens present in the gut lumen and is at the same time the triggering agent [1].

Keywords

Atopic Dermatitis Food Allergy Intestinal Permeability Sodium Cromoglycate Total Symptom Score 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Berlin Heidelberg 1989

Authors and Affiliations

  • L. Businco
  • A. Cantani
  • P. Meglio
  • P. G. Giampietro

There are no affiliations available

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