Advertisement

Relationship of Histamine Release and Other In Vitro Methods to Oral Provocation Test in Hen’s Egg Allergic Patients

  • S. Lau
  • U. Wahn
Conference paper

Abstract

The diagnosis of food allergy is difficult because of the complex composition of foods and the lack of standardized extracts for testing as well as the variety of symptoms which are hard to reproduce. Only about one-third of suspected adverse reactions to food are actually allergic, i. e. IgE-mediated [2]. A large percentage of patients with specific IgE and positive skin test do not show any symptoms upon food challenge [16].

Keywords

Atopic Dermatitis Food Allergy Histamine Release Allergy Clin Immunol Suspected Adverse Reaction 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Anet J, Bach JF, Baker RS, Bamett D, Burley RW, Howden MEH (1985) Allergens in white and yolk of hen’s egg. Int Arch Allergy Appl Immunol 77:364–371PubMedCrossRefGoogle Scholar
  2. 2.
    Bock SA, May CD (1983) Adverse reactions to food caused by sensitivity. In: Middleton E, Reed CF, Ellis E (eds) Allergy — principles and practice, 2nd edn, vol 2. Mosby, St Louis, pp 1415 ff chap 64Google Scholar
  3. 3.
    Bock SA, Lee W, Remigio LK, May CD (1978) Studies of hypersensitivity reaction to foods in infants and children. J Allergy Clin Immunol 62:327PubMedCrossRefGoogle Scholar
  4. 4.
    Clinton PM, Kemeny DM, Amlot P, Urbanek R, Lessof MH (1986) Histamine release from peripheral blood leukocytes in egg allergic patients. Clin Allergy 16: 345–354PubMedCrossRefGoogle Scholar
  5. 5.
    Dupont C, Molkhou P, Dehennin L (1987) Diagnosis of food allergy by measurement of intestinal permeability in children with atopic dermatitis. Fortythird annual meeting of the American Academy of Allergy and Immunology, Washington D.C., 19–25 FebruarGoogle Scholar
  6. 6.
    Fälth-Magnussen K, Kjellman NIM, Odelram H, Dundqvist T, Magnussen KE (1986) Gastrointestinal permeability in children with cow’s milk allergy: effect of milk challenge and sodium cromoglycate as assessed with polyethylene-glycols (PEG 400, PEG 1000). Clin Allergy 16:543–551CrossRefGoogle Scholar
  7. 7.
    Hattevig G, Kjellman B, Johannson SGO, Björksten B (1984) Clinical symptoms and IgE responses to common food proteins in atopic and healthy children. Clin Allergy 14:551–559PubMedCrossRefGoogle Scholar
  8. 8.
    Hill DJ, Davidson GP, Cameron DJS, Barnes GC (1979) The spectrum of cow’s milk allergy in childhood. Acta Paediatr Scan 68:847–852CrossRefGoogle Scholar
  9. 9.
    Hoffman DR (1983) Immunochemical identification of allergens in egg white. J Allergy Clin Immunol 71:481PubMedCrossRefGoogle Scholar
  10. 10.
    Kemeny DM, Urbanek R, Richards D, Greenall C (1987) Development of a semiquantitative enzyme-linked immunosorbent assay (ELISA) for detection of human IgG sublass antibodies. J Immunol Methods 96:47PubMedCrossRefGoogle Scholar
  11. 11.
    Langeland T (1982) A clinical and immunological study of allergy to hen’s egg white II. Antigen’s in hen’s egg white studied by Immunoelectrophoresis (CIE). Allergy 37:323–333PubMedCrossRefGoogle Scholar
  12. 12.
    Langeland T (1982) A clinical and immunological study of allergy to hen’s egg white III. Allergens in hen’s egg white studied by crossed radio-immunoelectrophoresis (CRIE). Allergy 37:521–530PubMedCrossRefGoogle Scholar
  13. 13.
    Langeland T, Harbitz O (1983) A clinical and immunological study of allergy to hen’s egg white IV. Purification and identification of a major allergen (antigen 22) in hen’s egg white. Allergy 38:131–139PubMedCrossRefGoogle Scholar
  14. 14.
    Maasch HJ, Fischer B, Wahl R, Wahn U (1984) Comparison of histamine release assay and RAST inhibition as tools for allergen extract standardization. Int Arch Allergy Appl Immunol 73:314–320PubMedCrossRefGoogle Scholar
  15. 15.
    Metcalfe DD (1984) Food hypersensitivity. J Allergy Clin Immunol 73(6):749–762PubMedCrossRefGoogle Scholar
  16. 16.
    Sampson HA (1983) Role of immediate food hypersensitivity in the pathogenesis in atopic dermatitis. J Allergy Clin Immunol 71:473PubMedCrossRefGoogle Scholar
  17. 17.
    Siraganian R (1974) An automated continuous flow system for the extraction and fluorometric analysis of histamine. Anal Biochem 57:393CrossRefGoogle Scholar
  18. 18.
    Conroy MC, Adkinson NF, Lichtenstein LM (1977) Measurements of IgE-and anti-IgE-induced histamine release. J Immunol 118(4):1317ffPubMedGoogle Scholar
  19. 19.
    Atikins AM, Steinberg SS, Metcalfe DD (1985) Evaluation of immediate adverse reaction to foods in adult patients, I Correlation of demographic laboratory and prick test data with response to controlled oral challenge. J Allergy Clin Immunol 348–355Google Scholar
  20. 20.
    May CD (1976) Objective clinical and laboratory studies of immediate hypersensitivity reactions to foods in asthmatic children. J Allergy Clin Immunol 58:500PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1989

Authors and Affiliations

  • S. Lau
  • U. Wahn

There are no affiliations available

Personalised recommendations