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Dysplasie-Karzinom-Sequenz

  • P. Hermanek
Conference paper

Zusammenfassung

Schon im 19. Jahrhundert erschienen in deutschen und englischen Zeitschriften Artikel, die Polypen des Dick- und Mastdarms als Vorläufer des Karzinoms diskutierten (Esmarch 1887; Lubarsch 1888; Bardenheuer 1891; Dalton 1893). Die erste morphologische Klassifikation kolorektaler Polypen im Hinblick auf unterschiedliche Risiken für maligne Entartung stammt von den deutschen Chirurgen Schmieden u. West- hues (1927). Erst in den 70er Jahren hat sich die grundlegende Unterscheidung zwischen neoplastischen und nichtneoplastischen Polypen (Morson u. Bussey 1970) allgemein durchgesetzt. Damit wurde die Polyp-Karzinom-Sequenz durch die Adenom- Karzinom-Sequenz abgelöst.

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© Springer-Verlag Berlin Heidelberg 1989

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  • P. Hermanek

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