Contact Urticaria and Allergic Contact Dermatitis to Constituents of Human Seminal Fluid
We describe a woman who suffered from coital vaginal burning and pain, rarely accompanied by genital and facial swelling. Six hours later genital erythema appeared. Fifteen hours after intercourse she observed painful vulvar erosions. Histology showed eczema. Local provocation with her partner’s fresh whole semen produced an erythemato-vesiculous eruption, which on histology showed eczema. Patch tests, scratch test and RAST for antibodies to human seminal plasma were negative. Lymphocyte transformation tests were positive with some fractions of her partner’s seminal fluid. History, clinical observation and test results favor the conclusion that there can be a coexistence of contact urticaria and allergic contact dermatitis to constituents of human semen.
Key wordsContact urticaria Allergic contact dermatitis Seminal fluid
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