Preliminary Findings on the Patterns of Epidermal Damage Induced by Irritants in Man
The histopathology of the primary irritant reactions induced after 48 h in human volunteers by benzalkonium chloride, sodium lauryl sulphate, croton oil, nonanoic acid, dithranol, and propylene glycol has been investigated. Patterns of epidermal damage were identified for each irritant, reflecting their differing chemical interactions with the cellular components of the skin.
Key wordsIrritant contact dermatitis Histopathology
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