Preliminary Findings on the Patterns of Epidermal Damage Induced by Irritants in Man

Willis, C. M.; Stephens, C. J. M.; Wilkinson, J. D.

doi:10.1007/978-3-642-74299-6_7

C. M. Willis⁶,
C. J. M. Stephens⁶ &
J. D. Wilkinson⁶

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8 Citations

Summary

The histopathology of the primary irritant reactions induced after 48 h in human volunteers by benzalkonium chloride, sodium lauryl sulphate, croton oil, nonanoic acid, dithranol, and propylene glycol has been investigated. Patterns of epidermal damage were identified for each irritant, reflecting their differing chemical interactions with the cellular components of the skin.

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References

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Authors and Affiliations

Department of Dermatology, Wycombe General Hospital, High Wycombe, Buckinghamshire, HP11 2TT, UK
C. M. Willis, C. J. M. Stephens & J. D. Wilkinson

Authors

C. M. Willis
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C. J. M. Stephens
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J. D. Wilkinson
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Editors and Affiliations

Hautklinik der Universität Heidelberg, Voßstraße 2, 6900, Heidelberg 1, Germany
Peter Frosch
Department of Medical Research (Dermatology), Katholieke Universiteit Leuven, 3000, Leuven, Belgium
A. Dooms-Goossens P.Ph., Ph.D.
Unit and Laboratory of Occupational and Environmental Dermatology, Catholic University of Louvain, 30, Clos Chapelle-aux-Champs, UCL 3033, 1200, Brussels, Belgium
J.-M. Lachapelle M. D. (Professor of Dermatology) (Professor of Dermatology)
St. John’s Hospital for Diseases of the Skin, Lisle Street, London, WC2H 7BJ, Great Britain
R. J. G. Rycroft
Department of Pathology, Free University Hospital, de Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands
R. J. Scheper

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Willis, C.M., Stephens, C.J.M., Wilkinson, J.D. (1989). Preliminary Findings on the Patterns of Epidermal Damage Induced by Irritants in Man. In: Frosch, P., Dooms-Goossens, A., Lachapelle, JM., Rycroft, R.J.G., Scheper, R.J. (eds) Current Topics in Contact Dermatitis. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-74299-6_7

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DOI: https://doi.org/10.1007/978-3-642-74299-6_7
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-74301-6
Online ISBN: 978-3-642-74299-6
eBook Packages: Springer Book Archive

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