Occupational Contact Dermatitis Due to Codiaeum Variegatum L., Chrysanthemum indicum L., Chrysanthemum x hortorum and Frullania dilatata L.

  • M.-B. Cleenewerck
  • P. Martin


This report describes a case of contact eczema in a driver-deliverer of plants and flowers. The evolution of his dermatitis was closely connected with this work. Patch tests showed positive reactions to Codiaeum variegatum (L.) A.Juss.var. pictum (Lodd.) Müll. Arg., cultivars Excellent, Mrs Iceton and Norma, to Chrysanthemum indicum L., Chrysanthemum x hortorum, Frullania dilatata L. and to balsam of Peru. Patch test results were also positive to water, methanol and ethyl acetate extracts of the leaves of the cultivar Excellent but negative to a hexane extract. Therefore, hypersensitivity included some plants that belong to three different families : Euphorbiaceae, Compositae and Hepaticae. Contact allergy to Chrysanthemum and to Frullania is well known. A few cases of allergic contact dermatitis due to Codiaeum variegatum have been described in the literature. This plant, often called florists croton, should not be confused with Croton tiglium L., or croton oil plant, which is a strong irritant to the skin. This case focused our attention on the difficulty of skin protection and the serious problem concerning the patient’s occupational future.

Key words

Occupational plant dermatitis Codiaeum allergy Chrysanthemum allergy Frullania dilatata allergy Plant extracts 


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  1. 1.
    Agrup G (1969) Hand eczema and other hand dermatoses in South Sweden. Acta Derm Venereol 49(Suppl 61): 57.Google Scholar
  2. 2.
    Benezra C, Ducombs G, Sell Y, Foussereau J (1985) Plant contact dermatitis. Decker and Mosby, Toronto, pp 162–163.Google Scholar
  3. 3.
    Frerichs G, Arends G, Zörnig H (1938) Hagers Handbuch der Pharmazeutischen Praxis, 2nd edn, vol 2, p 1124. Springer.Google Scholar
  4. 4.
    Gonçalo S (1987) Contact sensitivity to lichens and compositae in Frullania dermatitis. Contact Dermatitis 16: 84–86.PubMedCrossRefGoogle Scholar
  5. 5.
    Hausen BM, Schulz KH (1977) Occupational contact dermatitis due to Croton (Codiaeum variegatum (L.) A.Juss.var. pictum(Lodd.) Muell. Arg.). Contact Dermatitis 3: 289-2.PubMedCrossRefGoogle Scholar
  6. 6.
    Hendrickson JB (1959) Stereochemical implications in sesquiterpene biogenesis. Tetrahedron 7: 82–89.CrossRefGoogle Scholar
  7. 7.
    Hjorth N (1961) Eczematous allergy to balsams. Munksgaard, Copenhagen.Google Scholar
  8. 8.
    Hjorth N (1970) Active sensitisation with alantolactone. Contact Dermatitis Newsletter 8: 175.Google Scholar
  9. 9.
    Lynne-Davies G, Mitchell JC (1974) Patch tests for irritancy — some common house plants. Contact Dermatitis Newsletter 16: 501–502.Google Scholar
  10. 10.
    Schmidt H, Ølholm-Larsen P (1977) Allergic contact dermatitis from Croton (Codiaeum). Contact Dermatitis 3: 100.Google Scholar
  11. 11.
    Tafelkruyer J, Van Ketel WG (1976) Sensitivity to Codiaeum variegatum. Contact Dermatitis 2: 288.PubMedCrossRefGoogle Scholar
  12. 12.
    Van Ketel WG (1979) Occupational contact dermatitis due to Codiaeum variegatum and possibly to Aeschynantus Pulcher. Derm Beruf Umwelt 27: 141–142.PubMedGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1989

Authors and Affiliations

  • M.-B. Cleenewerck
    • 1
  • P. Martin
    • 2
  1. 1.Comité pour le Développement de la Médecine du TravailLille CedexFrance
  2. 2.Clinique Dermatologique C. H. R.Hôpital Claude HuriezLille CedexFrance

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