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Preliminary Results on the Effectiveness of Two Forms of Fragrance Mix as Screening Agents for Fragrance Sensitivity

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Current Topics in Contact Dermatitis

Summary

2455 consecutive patch test patients were tested to two separate fragrance mixes: one the standard 8% Hermal/Larsen fragrance mix and the other a new 9.5% Hausen mix containing dihydrocoumarin and citral but excluding oak moss and amyl cinnamaldehyde. The overall incidences of allergy to fragrance materials as measured by these mixes were 7.8% and 6.7%, respectively. There was relatively poor concordance between the mixes which could not be explained only by their different composition. False-positive reactions and false-negative reactions occurred with both types of mix. The 9.5% Hausen mix gave rather more unexplained positive results but both dihydrocoumarin and citral were found to give significant numbers of positive reactions.

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References

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Author information

Authors and Affiliations

  1. Department of Dermatology, Wycombe General Hospital, High Wycombe, Buckinghamshire, HP11 2TT, UK

    J. D. Wilkinson

  2. Department of Dermatology, Algade 33, DK-4000, Roskilde, Denmark

    K. Andersen

  3. Department of Dermatology, Hospital de N.S. del Mar, Paseo Maritimo S/n, 08003, Barcelona, Spain

    J. Camarasa

  4. Service de Dermatologie, Hopital Pellegrin, Place Amélie Raba-Leon 33076, Bordeaux Cedex, France

    G. Ducombs

  5. Abteilung Dermatologie, Ruprecht-Karls-Universität Heidelberg, Voßstraße 2, D-6900, Heidelberg 1, West Germany

    P. Frosch

  6. Department of Dermatology, University of Oulu, SF-90220, Oulu 22, Finland

    A. Lahti

  7. Department of Dermatology, Kas-Gentofte, N.Andersenvej, 63, DK-2900, Hellerup, Denmark

    T. Menné

  8. St. John’s Hospital for Diseases of the Skin, 5 Lisle Street, London, WC2H 7BJ, UK

    R. J. G. Rycroft & I. White

Authors
  1. J. D. Wilkinson
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  2. K. Andersen
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  3. J. Camarasa
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  4. G. Ducombs
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  5. P. Frosch
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  6. A. Lahti
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  7. T. Menné
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  8. R. J. G. Rycroft
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  9. I. White
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Editor information

Editors and Affiliations

  1. Hautklinik der Universität Heidelberg, Voßstraße 2, 6900, Heidelberg 1, Germany

    Peter Frosch

  2. Department of Medical Research (Dermatology), Katholieke Universiteit Leuven, 3000, Leuven, Belgium

    A. Dooms-Goossens P.Ph., Ph.D.

  3. Unit and Laboratory of Occupational and Environmental Dermatology, Catholic University of Louvain, 30, Clos Chapelle-aux-Champs, UCL 3033, 1200, Brussels, Belgium

    J.-M. Lachapelle M. D. (Professor of Dermatology) (Professor of Dermatology)

  4. St. John’s Hospital for Diseases of the Skin, Lisle Street, London, WC2H 7BJ, Great Britain

    R. J. G. Rycroft

  5. Department of Pathology, Free University Hospital, de Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands

    R. J. Scheper

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© 1989 Springer-Verlag Berlin Heidelberg

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Wilkinson, J.D. et al. (1989). Preliminary Results on the Effectiveness of Two Forms of Fragrance Mix as Screening Agents for Fragrance Sensitivity. In: Frosch, P., Dooms-Goossens, A., Lachapelle, JM., Rycroft, R.J.G., Scheper, R.J. (eds) Current Topics in Contact Dermatitis. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-74299-6_24

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  • DOI: https://doi.org/10.1007/978-3-642-74299-6_24

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-74301-6

  • Online ISBN: 978-3-642-74299-6

  • eBook Packages: Springer Book Archive

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