Remote Functionalization of Carbon-Hydrogen and Carbon-Carbon Bonds by Bare Transition Metal Ions in the Gas Phase

  • Gregor Czekay
  • Thomas Drewello
  • Karsten Eller
  • Carlito B. Lebrilla
  • Tilmann Prüsse
  • Christian Schulze
  • Norbert Steinrück
  • Detlev Sülzle
  • Thomas Weiske
  • Helmut Schwarz
Conference paper

Abstract

The selective functionaIization of C-H bonds remains one of the major focuses of catalytic and organic chemistry. High selectivity is often achieved by the presence of activating groups which induce the reactivity of the neighbouring C-H bonds by, for example, polarizing the bond, thus making the hydrogen more acidic, or by generally weakening the C-H bond. The selective functionalization of hydrocarbon segments of a molecule remote from any functional group represents a great challenge. While such reactions are common to enzymes which coordinate a functional group and geometrically select a specific section of the molecule (see, for example, the enzymatic conversion of stearic to oleic acid. Scheme 1), only a few cases in solution chemistry are reported [1] where a similar principle seems to be operative.

Keywords

Migration Nitri aLkanes nitriLes aLkynes 

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Copyright information

© Springer-Verlag Berlin Heidelberg 1989

Authors and Affiliations

  • Gregor Czekay
    • 1
  • Thomas Drewello
    • 1
  • Karsten Eller
    • 1
  • Carlito B. Lebrilla
    • 1
  • Tilmann Prüsse
    • 1
  • Christian Schulze
    • 1
  • Norbert Steinrück
    • 1
  • Detlev Sülzle
    • 1
  • Thomas Weiske
    • 1
  • Helmut Schwarz
    • 1
  1. 1.Institut für Organische Chemie der Technischen Universität BerlinBerlin 12Germany

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