Islet Amyloid and Type 2 Diabetes

  • P. Westermark
Conference paper
Part of the Bayer AG Centenary Symposium book series (BAYER)


The pathologic alterations of the pancreas in type 2 diabetes are more discrete than in type 1 diabetes. It has therefore been claimed, even quite recently, that the morphology of the islets is normal in this maturity form of the disease. However, there are some changes which are typical of type 2 diabetes and demonstrable in most, although not all cases. The most constant of these changes is probably deposition of amyloid in the islets of Langerhans.


Amyloid Fibril Amyloid Protein Islet Amyloid Polypeptide Staining Property Nondiabetic Individual 
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© Springer-Verlag Berlin Heidelberg 1989

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  • P. Westermark

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