Abstract
The genetically obese Zucker rat, characterized by the presence of the double recessive gene fa is a model of obesity and insulin resistance. It has a moderate hyperglycemia, and an abnormal oral glucose tolerance [1]. Ultimately, it develops ocular complications [2]. It thus represents a potential model of at least some aspects of noninsulin-dependent diabetes mellitus (NIDDM).
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References
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© 1989 Springer-Verlag Berlin Heidelberg
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Jeanrenaud, B. (1989). Physiopathology and Possible Etiology of Hormonal Dysregulations and Insulin Resistance in Obese Rats: a Potential Model for Some Human Obesity. In: Creutzfeldt, W., Lefèbvre, P.J. (eds) Diabetes Mellitus: Pathophysiology and Therapy. Bayer AG Centenary Symposium. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-74255-2_11
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DOI: https://doi.org/10.1007/978-3-642-74255-2_11
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