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Abnormal Glucagon Secretion in Type 2 (Noninsulin-Dependent) Diabetes Mellitus: Causes and Consequences

  • J. E. Gerich
Part of the Bayer AG Centenary Symposium book series (BAYER)

Abstract

Insulin and glucagon are generally acknowledged to be the most important hormones responsible for the moment-to-moment control of plasma glucose concentrations in man [41]. This is due to their immediate antagonistic effects on the liver; insulin suppresses hepatic glucose output and glucagon stimulates hepatic glucose output. Moreover, secretion of these hormones is reciprocally regulated by glucose; an increase in arterial glucose stimulates insulin secretion and suppresses glucagon secretion, whereas a decrease in arterial glucose suppresses insulin secretion and stimulates glucagon secretion [15].

Keywords

Glucagon Secretion Postprandial Hyperglycemia Plasma Glucagon Nondiabetic Subject Hepatic Glucose Output 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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© Springer-Verlag Berlin Heidelberg 1989

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  • J. E. Gerich

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