Identification and Function of Bile Salt Binding Polypeptides of Hepatocyte Membrane

  • Gerhart Kurz
  • Michael Müller
  • Ursula Schramm
  • Wolfgang Gerok
Conference paper
Part of the Proceedings in Life Sciences book series (LIFE SCIENCES)

Abstract

In the course of their enterohepatic circulation bile salts are taken up through the sinusoidal and secreted through the canalicular membrane of the hepatocyte. In these different membrane domains different bile-salt- binding polypeptides are present, as demonstrated unequivocally by photo-affinity-labelling studies (Kramer et al., 1982; Buscher et al., 1987; Fricker et al., 1987). All these binding polypeptides could somehow be involved in hepatobiliary bile salt transport.

Keywords

Albumin Polypeptide Photolysis Carbene Cholan 

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References

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Copyright information

© Springer-Verlag Berlin Heidelberg 1989

Authors and Affiliations

  • Gerhart Kurz
    • 1
  • Michael Müller
    • 1
  • Ursula Schramm
    • 1
  • Wolfgang Gerok
    • 1
  1. 1.Institut für Organische Chemie und Biochemie und Medizinische KlinikUniversität FreiburgFreiburg i. Br.Germany

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