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Metastasis: The Clinical Problem

  • Conference paper
Cancer Metastasis

Abstract

The clinical problem is that metastasis causes most of the therapeutic failures from the common solid neoplasms. This paper will attempt first to describe the magnitude of the metastasis problem using common solid neoplasms as examples, next to focus on the problem of defining metastatic potential, including a brief discussion of recent DNA analyses in relation to prognosis, then to describe some of the characteristics of the biology of metastasis as observed by clinicians, the mechanisms of which could be hypothetically exploited in future therapies, and finally to challenge the researcher/clinician with some of the major problems in metastasis therapy.

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Author information

Authors and Affiliations

  1. Miami Cancer Institute, USA

    E. V. Sugarbaker (Director Surgical Oncology, Co-director Oncology Laboratory)

  2. Cedars Medical Center, USA

    E. V. Sugarbaker (Director Surgical Oncology, Co-director Oncology Laboratory) & D. N. Seckinger (Co-director Oncology Laboratory)

  3. Oncology Laboratory, Cedars Medical Center, USA

    O. O. Frankfurt (Research Director)

Authors
  1. E. V. Sugarbaker
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  2. D. N. Seckinger
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  3. O. O. Frankfurt
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Editor information

Editors and Affiliations

  1. Institut für Immunologie und Genetik, DKFZ, Im Neuenheimer Feld 280, D-6900, Heidelberg, Germany

    Volker Schirrmacher  & Reinhard Schwartz-Albiez  & 

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© 1989 Springer-Verlag Berlin Heidelberg

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Sugarbaker, E.V., Seckinger, D.N., Frankfurt, O.O. (1989). Metastasis: The Clinical Problem. In: Schirrmacher, V., Schwartz-Albiez, R. (eds) Cancer Metastasis. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-74236-1_1

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  • DOI: https://doi.org/10.1007/978-3-642-74236-1_1

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-50471-9

  • Online ISBN: 978-3-642-74236-1

  • eBook Packages: Springer Book Archive

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