Route of Administration is a Determinant of the Tissue Disposition and Effects of TBTO on Cytochrome P-450-Dependent Drug Metabolism

  • Daniel W. Rosenberg
Conference paper
Part of the NATO ASI Series book series (volume 37)


Organotins have found wide industrial and agricultural applications as a result of the potent biocidal activities exhibited by many of these compounds (1,2). Recently, some of these compounds have undergone testing for potential antitumor activity (3). This wide diversity of applications of organotins has prompted an extensive evaluation of their general toxicity (4–7).


Heme Oxygenase Graphite Furnace Atomic Absorption Spectroscopy Organotin Compound Heme Oxygenase Activity Small Intestinal Epithelium 
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Copyright information

© Springer-Verlag Berlin Heidelberg 1990

Authors and Affiliations

  • Daniel W. Rosenberg
    • 1
  1. 1.The Rockefeller University HospitalNew YorkUSA

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