Function of GMG Cells
The use of the term “metrial gland” over the years to describe the mesometrial region of the uterus in which GMG cells appear during pregnancy has implied that a secretory function is to be expected. Classical extirpation experiments, however, to analyse its “glandular” function have not been carried out and, indeed, the arrangement of the blood vessels passing through the metrial gland to and from the placenta means that surgical excision of the gland is not feasible. In view of the circumstantial nature of the evidence which led to the adoption of the word “gland”, it is probably better to ignore the term and any preconceptions it might have associated with it and to consider instead all the information available about the appearance, composition and distribution of GMG cells in attempting to determine their function.
KeywordsTrypan Blue Trophoblast Cell Maternal Tissue Maternal Immune Response Decidua Basalis
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