Pharmacology of a Locust Thoracic Ganglion Somal Nicotinic Acetylcholine Receptor

  • Jack A. Benson
Part of the NATO ASI Series book series (volume 25)

Abstract

The dramatic increase in the number of highly-specific new receptor-binding drugs together with a flood of receptor amino acid sequences has revealed differences among receptor types hitherto thought to be virtually identical, as well as new relationships among apparently dissimilar receptor families. These new observations are forcing a re-evaluation of the old pharmacological classifications and raising interesting questions about the evolution and variation of receptor families in the different animal groups (Venter et al 1988). Our interest is in the receptors and ion channels of the insects and other arthropods, and how they compare pharmacologically and functionally with those of the vertebrates.

Keywords

Nicotine Choline Acetylcholine Piperazinium Tetraethyl 

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Copyright information

© Springer-Verlag Berlin Heidelberg 1988

Authors and Affiliations

  • Jack A. Benson
    • 1
  1. 1.R&D Plant Protection, Agricultural DivisionCIBA-GEIGY Ltd.BaselSwitzerland

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