Acetylcholinesterase Activity and Alpha-Bungarotoxin Binding in the Inner Retina of a Marine Teleost

  • S. Deplano
Conference paper
Part of the NATO ASI Series book series (volume 31)


Acetylcholine (ACh) is accepted as a retinal neurotransmitter, and a specific class of amacrine cells in mammals have been elucidated as cholinergic neurons (Masland et al., 1984, Voigt, 1986). Specific identification of such neurons provides new impetus for an investigation both of the enzymes involved in the cholinergic system (e.g., the ACh-hydrolyzing enzyme, and acetylcholinesterase, AChE) and of the locations of acetylcholine receptors.


Ganglion Cell Amacrine Cell Retinal Neuron Marine Teleost Laminar Distribution 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. Chang CC, Lee Y (1963) Isolation of neurotoxin from the venom of Bungarus multicinctus and their modes of neuromuscular blocking action. Archs Int Pharmacody 144: 241–257Google Scholar
  2. Famiglietti EV (1987) Starburst amacrine cells in cat retina are associated with bistratified presumed directionally selective, ganglion cells. Brain Res 413: 404–408PubMedCrossRefGoogle Scholar
  3. Freeman JA, Schmidt JT, Oswald RE (1980) Effect of alpha-bungarotoxin in retino-tectal synaptic transmission in goldfish and toad. Neuroscience 5: 929–942PubMedCrossRefGoogle Scholar
  4. Hayashi T (1980) Histochemical localization of dopamine and acetyl cholinesterase activity in the carp retina. Acta Histochem Cytochem 13: 330–342CrossRefGoogle Scholar
  5. Henley JM, Mynlieff M, Lindstrom JM, Oswald RE (1986) Interaction of monoclonal antibodies to electroplaque acetylcholine receptors with the α-bungarotoxin binding site of goldfish brain. Brain Res 364: 405–412PubMedCrossRefGoogle Scholar
  6. Karnowsky MJ, Roots L (1964) A “direct coloring” thiocholine method for cholinesterase. J Histochem Cytochem 12: 219–221CrossRefGoogle Scholar
  7. Neal MJ (1983) Cholinergic mechanisms in the vertebrate retina. In: Osborne N, Chader G (eds) Progress in Retinal Research 2, Pergamon Press, Oxford, 191–212Google Scholar
  8. Pourcho RG (1979) Localization of cholinergic synapses in mammalian retina with peroxidase conjugated α-bungarotoxin. Vision Res 19: 287–293PubMedCrossRefGoogle Scholar
  9. Pourcho RG, Osman K (1986) Acetylcholinesterase localization in cat retina: a comparison with choline acetyltransferase. Exp Eye Res 43: 585–594PubMedCrossRefGoogle Scholar
  10. Tumosa N, Eckenstein F, Stell WK (1984) Immunocytochemical localization of putative cholinergic neurons in the goldfish retina. Neurosci Lett 48: 255–259PubMedCrossRefGoogle Scholar
  11. Vallerga S, Deplano S (1984) Differentiation, extent and layering of amacrine cells in the retina of a spar id fish. Proc R Soc Lond B 221: 465–477PubMedCrossRefGoogle Scholar
  12. Voigt T (1986) Cholinergic amacrine cells in the rat retina. J Comp Neurol 248: 19–35PubMedCrossRefGoogle Scholar
  13. Zucker C, Yazulla S (1982) Localization of synaptic and nonsynaptic nicotinic-acetylcholine receptors in the goldfish retina. J Comp Neurol 204: 188–195PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1989

Authors and Affiliations

  • S. Deplano
    • 1
  1. 1.Institute of Comparative AnatomyUniversity of GenoaGenovaItaly

Personalised recommendations