Serotonergic Cells in the Chicken Retina
Although sertonin-accumulating cells have been found in the retinas of most vertebrate species (Osborne ’84; Redburn ’5), it is only in non-mammals that endogenous serotonin (5HT) has been detected by immunohistochemical techniques (Weiler & Schutte ’85a, ’85b; Schutte & Weiler ’87; Millar et al ’87). Consequently there is controversy over the role of 5HT as a retinal neurotransmitter. Commonly, only 5HT-accumulating amacrine cells have been detected but in a few species 5HT-accumulating bipolar cells have also been reported (Osborne ’85; Sandell & Masland ’86). In the turtle and chicken, serotonin-like immunoreactivity (5HTLI) has been found in subpopulations of both amacrine and bipolar cells without preloading or other pharmacological manipulation of the retina (Weiler & Schutte ’85a; Millar et al ’87).
KeywordsBipolar Cell Amacrine Cell Horizontal Cell Inner Nuclear Layer Inner Plexiform Layer
Unable to display preview. Download preview PDF.
- Holmgren-Taylor I (1983) Synaptic organization of the indoleamine-accumulating neurons in the cyprinid retina. Cell Tiss Res 229: 317–335.Google Scholar
- Ishimoto I, Millar TJ, Chubb IW, Morgan IG (1986) Somatostatin-immunoreactive amacrine cells of the chicken retina: retinal mosaic, ultrastructural features, and light-driven variations in peptide metabolism Neurosci 17: 1217–1233.Google Scholar
- Lasansky A (1978) Contacts between receptors and electrophysiologically identified neurones in the retina of the larval tiger salamander. J Physiol(Lond) 285: 531–542.Google Scholar
- Osborne NN (1984) Indoleamines in the eye with special reference to the serotonergic neurones of the retina. In: Osborne NN, Chader GJ (eds) Progress in Retinal Research. Vol 3. Oxford, Pergammon Press, p61.Google Scholar
- Redburn DA (1985) Serotonin neurotransmitter systems in vertebrate retina. In: Morgan WW (ed) Retinal Transmitters and Modulators: Models for the Brain. Vol.11. Florida: CRC Press, pl07.Google Scholar