Membrane Currents of Retinal Bipolar Cells: Goldfish vs. Mouse
The time course of light-evoked responses differs greatly between neurons of the distal retina and the proximal retina. In the distal retina, photoreceptors, horizontal cells and bipolar cells show sustained light responses, while in the proximal retina responses of amacrine and ganglion cells have prominent transient components even in those cells classified as a sustained type. Shaping of signals from sustained to transient may involve various mechanisms; activation of specific membrane conductances of amacrine and ganglion cells, interaction between excitatory and inhibitory signals that arrive to a postsynaptic cell with time delay, or a transient release of transmitter substance from presynaptic (bipolar) cells.
KeywordsGanglion Cell Bipolar Cell Pipette Solution Horizontal Cell Tail Current
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