Abstract
In spite of its importance to a number of scientific disciplines, there are few reliable techniques for the estimation of the aqueous solubility of a crystalline organic compound. One of the major reasons for the lack of progress in this field is the fact that solubility is not strictly an additive, constituative property, and thus cannot be predicted by group contributions alone.
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© 1988 Springer-Verlag Berlin Heidelberg
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Yalkowsky, S.H. (1988). Estimation of the Aqueous Solubility of Organic Compounds. In: Jochum, C., Hicks, M.G., Sunkel, J. (eds) Physical Property Prediction in Organic Chemistry. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-74140-1_27
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DOI: https://doi.org/10.1007/978-3-642-74140-1_27
Publisher Name: Springer, Berlin, Heidelberg
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