Current Problems in Quantitative Structure Activity Relationships
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Quantitative structure activity relationships (QSAR) are to be understood as a consequence of the fact that the interactions of drugs with their biological counterparts are determined by intermolecular forces. Thus the structural dependence of biological activities can be described either by physicochemical parameters (Hansch analysis) or by indicator variables encoding different structural features (Free Wilson analysis, pattern recognition).
KeywordsQuantitative Structure Activity Relationship Quantitative Structure Activity Relationship Bilinear Model Parabolic Model Enzyme Inhibitor Complex
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