Metals — Epidemiological and Experimental Evidence for Carcinogenicity

  • R. R. Lauwerys
Part of the Archives of Toxicology book series (TOXICOLOGY, volume 13)


This paper mainly summarizes the epidemilogical evidence regarding the carcinogenicity of some metals. It may therefore be useful to recall the ideal requirements for establishing carcinogenicity from epidemiological evidence. Briefly, the positive association between exposure and cancer should not be explicable by bias in recording or detection, confounding or chance; it should vary appropriately with intensity and duration of exposure and time after exposure begins and ends and it should be observed repeatedly in different circumstances (Doll 1985).


Cobalt Oxide Arsenic Exposure Arsenic Trioxide Cobalt Sulfide Antimony Trioxide 
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Copyright information

© Springer-Verlag Berlin Heidelberg 1989

Authors and Affiliations

  • R. R. Lauwerys
    • 1
  1. 1.Unité de Toxicologie Industrielle et Médecine du Travail, Faculté de MédecineUniversité Catholique de LouvainBruxellesBelgique

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