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Physiological Concepts of Cardiovascular and Respiratory Control: Theoretical Basis and Applicability in Man

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Innovations in Physiological Anaesthesia and Monitoring

Abstract

Key concepts of the present symposium are: anaesthesia — physiology — internal medicine — innovation. What are the relationships among these concepts? We believe one of the innovations to lie precisely in their combination. Internal medicine, and especially anaesthesia, is to a considerable extent applied physiology. The still too rigid borders between the disciplines, especially in Germany, must be overcome to make the concepts and methods developed in one field fruitful for application in other fields. This is especially important for the application of basic physiological concepts to man. In this context we will confine our attention to one central point of view, that of neurovegetative regulation, in particular of the cardiovascular and respiratory systems. The term neurovegetative means neuronal regulation of the functions of vegetative organs and organ systems. Within this general framework the cardiovascular and respiratory regulatory systems form part of an interacting complex of many kinds of regulatory processes.

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References

  1. Abel HH, Klüßendorf D, Koepchen HP (1985) Pattern of somato-vegetative innervation in healthy humans during rest and mental load. Pflugers Arch [Suppl] 403: R51

    Google Scholar 

  2. Abel HH, Klüßendorf D, Koepchen HP (1985) Interaction of behavioural and chemical drive in ventilation and respiratory pattern during and after mental load in human subjects. Pflugers Arch [Suppl 2] 405: R50

    Article  Google Scholar 

  3. Abel HH, Klüßendorf D, Krause R, Koepchen HP (1985) Are enhanced respiratory oscillations of heart rate at rest in endurance-trained sportsmen related primarily to increased vagal tone? J Interdiscip Cycle Res 16: 240

    Google Scholar 

  4. Abel HH, Klüßendorf D, Koepchen HP (1986) Relations between spontaneous events in autonomic and respiratory innervation patterns in man. Pflugers Arch [Suppl] 406: R22

    Google Scholar 

  5. Angelone A, Coulter NA Jr (1964) Respiratory sinus arrhythmia: a frequency dependent phenomenon. J Appl Physiol 19: 479–482

    PubMed  CAS  Google Scholar 

  6. Cohen MI (1979) Neurogenesis of respiratory rhythm in the mammal. Physiol Rev 59 (4): 1105–1173

    PubMed  CAS  Google Scholar 

  7. Eckoldt K, Braun W, Lange V (1985) Heart rate at different autonomic states. J Interdiscip Cycle Res 16 (4): 252–253

    Google Scholar 

  8. Euler C von (1986) Brain stem mechanisms for generation and control of breathing pattern. In: Fishman AP, Cherniack NS, Widdicombe JG, Geiger SR (eds) The respiratory system. American Physiological Society, Bethesda, pp 1–67 (Handbook of physiology, sect 3, vol 2 )

    Google Scholar 

  9. Gauer OH, Henry JP (1963) Circulatory basis of fluid volume control. Physiol Rev 43: 423–481

    PubMed  CAS  Google Scholar 

  10. Golenhofen K, Hildebrandt G (1957) Über spontanrhythmische Schwankungen der Muskeldurchblutung des Menschen. Z Kreislaufforsch 46: 257

    PubMed  CAS  Google Scholar 

  11. Heinemann H, Stock G, Schaefer H (1973) Temporal correlations of responses in blood pressure and motor reaction under electrical stimulation of limbic structures in unanaesthetized, unrestrained cats. Pflugers Arch 343: 27–40

    Article  PubMed  CAS  Google Scholar 

  12. Kenner T (1971) Dynamic control of flow and pressure in the circulation. Kybernetik 9: 215

    Article  PubMed  CAS  Google Scholar 

  13. Koch E (1931) Die reflektorische Selbststeuerung des Kreislaufs. Steinkopff Dresden

    Google Scholar 

  14. Koepchen HP (1962) Die Blutdruckrhythmik. Steinkopff, Darmstadt

    Google Scholar 

  15. Koepchen HP (1969) Vegetative-somatic relationships in single neuron activity in the lower brain stem. In: Evans CR, Mulholland TB (eds) Attention in neurophysiology. Butterworth, London, pp 83–99

    Google Scholar 

  16. Koepchen HP (1972) Kreislaufregulation. In: Gauer O, Kramer K, Jung R (eds) Physiologie des Menschen, vol 3. Urban and Schwarzenberg, Munich, pp 327–406

    Google Scholar 

  17. Koepchen HP (1975) Atmungsregulation. In: Gauer O, Kramer K, Jung R (eds) Physiologie des Menschen, 2nd edn, vol 6. Urban and Schwarzenberg, Munich, pp 163–310

    Google Scholar 

  18. Koepchen HP (1983) Respiratory and cardiovascular “centres”: functional entirety or separate structures. In: Schlaefke ME, Koepchen HP, See WR (eds) Central neurone environment and the control systems of breathing and circulation. Springer, Berlin Heidelberg New York, pp 221–237

    Google Scholar 

  19. Koepchen HP (1984) History of studies and concepts of blood pressure waves. In: Miyakawa K, Koepchen HP, Polosa C (eds) Mechanisms of blood pressure waves. Japan Scientific Societies, Tokyo; Springer, Berlin Heidelberg New York, pp 3–23

    Google Scholar 

  20. Koepchen HP, Lazar H, Borchert J (1974) On the role of the nucleus infrasolitarius in the determination of respiratory periodicity. Proc IUPS Vol. IX, p. 81

    Google Scholar 

  21. Koepchen HP, Langhorst P, Seller H (1975) The problem of identification of autonomic neurons in the lower brain stem. Brain Res 87: 373–393

    Article  Google Scholar 

  22. Koepchen HP, Hilton SM, Trzebski A (eds) (1980) Central interaction between respiratory and cardiovascular control systems. Springer, Berlin Heidelberg New York

    Google Scholar 

  23. Koepchen HP, Klüßendorf D, Sommer D (1981) Neurophysiological background of central neural cardiovascular-respiratory coordination: basic remarks and experimental approach. J Auton Nerv Syst 3: 335–368

    Article  PubMed  CAS  Google Scholar 

  24. Koepchen HP, Abel HH, Klüßendorf D (1985) Heart-rate dynamics in healthy humans before, during and after a mental test. Pflugers Arch [Suppl 2] 405: R50

    Article  Google Scholar 

  25. Koepchen HP, Lazar H, Klüßendorf D, Hukuhara T (1986) Medullary apneusis by lesions and cooling in the ventrolateral solitary tract region and genesis of respiratory rhythm J Auton Nerv Syst, (Suppl. pp. 63–69)

    Google Scholar 

  26. Langhorst P, Schulz B, Schulz G, Lambertz M (1983) Reticular formation of the lower brainstem. A common system for cardiorespiratory and somatomotor functions: discharge patterns of neighbouring neurons influenced by cardiovascular and respiratory afferents. J Auton Nerv Syst 9: 411–432

    Article  PubMed  CAS  Google Scholar 

  27. Litter WA, Honour J, Pugsley DJ, Sleight P (1975) Continuous recording of direct arterial pressure in unrestricted patients. Its role in the diagnosis and management of high blood pressure. Circulation 51: 1101–1106

    Google Scholar 

  28. Loeschcke HH (1960) Homoiostase des arteriellen CO2-Druckes und Anpassung der Lungenventilation an den Stoffwechsel als Leistungen eines Regelsystems. Klin Wochenschr 38: 366

    Article  PubMed  CAS  Google Scholar 

  29. Loeschcke HH (1982) Central chemosensitivity and reaction theory. J Physiol 332: 1–24

    PubMed  CAS  Google Scholar 

  30. Loeschcke HH, Koepchen HP (1958) Versuch zur Lokalisation des Angriffsortes der Atmungs-und Kreislaufwirkung von Novocain im Liquour cerebrospinalis. Pflugers Arch 266: 628–641

    Article  PubMed  CAS  Google Scholar 

  31. Magoun HW (1950) Caudal and cephalic influences of the brain stein reticular formation. Physiol Rev 30: 459–474

    PubMed  CAS  Google Scholar 

  32. Malliani A, Lombardi F, Pagani M, Cerutti S (1986) The problem of approaching the sympathetic and vagal “tone”. J Auton Nerv Syst, Suppl. pp. 191–196

    Google Scholar 

  33. Mancia G, Ferrari A, Gregorini L, Parati G, Pomidossi G, Bertinieri G, Grassi G et al. (1983) Blood pressure and heart rate variabilities in normotensive and hypertensive human beings. Circ Res 33: 96–104

    Google Scholar 

  34. Mittelstaedt H (ed) (1954) Regelungsvorgänge in der Biologie. Oldenbourg, Darmstadt

    Google Scholar 

  35. Richter DW (1982) Generation and maintenance of respiratory rhythm. J Exp Biol 100: 93–107

    PubMed  CAS  Google Scholar 

  36. Schlaefke ME (1981) Central chemosensitivity: a respiratory drive. Rev Physiol Biochem Pharmacol 90: 171–244

    Article  PubMed  CAS  Google Scholar 

  37. Schlomka G, Reindell H (1936) Untersuchungen über die physiologische Unregelmäßigkeit des Herzschlages. Z Kreislaufforsch 28: 473–492

    Google Scholar 

  38. Seller H, Langhorst P, Polster J, Koepchen HP (1967) Zeitliche Eigenschaften der Vasomotorik. II. Erscheinungsformen und Entstehung spontaner und nervös induzierter Gefäßrhythmen. Pflugers Arch 296: 110–132

    Google Scholar 

  39. Wagner R (1954) Beispiele und Probleme biologischer Regelung. Thieme, Stuttgart

    Google Scholar 

  40. Weigelt H, Lübbers DW (1984) The fine adjustment of capillary blood flow through excitation of the capillary wall. In: Lübbers DW, Acker H, Leniger-Follert E, Goldstick TK (eds) Oxygen transport to tissue V. Plenum, New York, pp 731–737

    Google Scholar 

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© 1989 Springer-Verlag Berlin Heidelberg

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Koepchen, H.P., Abel, HH., Klüssendorf, D. (1989). Physiological Concepts of Cardiovascular and Respiratory Control: Theoretical Basis and Applicability in Man. In: Droh, R., Spintge, R. (eds) Innovations in Physiological Anaesthesia and Monitoring. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-74114-2_1

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  • DOI: https://doi.org/10.1007/978-3-642-74114-2_1

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-50331-6

  • Online ISBN: 978-3-642-74114-2

  • eBook Packages: Springer Book Archive

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