Measurement of Skin Thickness, Wealing, Irritant, Immune and Ultraviolet Inflammatory Response in Skin

  • P. M. Farr
  • C. M. Lawrence
  • S. Shuster
Part of the Handbook of Experimental Pharmacology book series (HEP, volume 87 / 2)


Measurement of skin and lesion thickness is one of the few objective ways of measuring the cutaneous response to inflammatory and therapeutic agents in humans. The three techniques described here measure epidermal and dermal thickness, although the normal epidermis contributes only about 5%. Variation in skin thickness occurs with site, age and sex and is due principally to differences in dermal collagen layer (Shuster et al. 1975).


Skin Thickness Pulse Transit Time Visual Grade Minimal Erythema Dose Reflectance Spectrophotometry 
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Copyright information

© Springer-Verlag Berlin Heidelberg 1989

Authors and Affiliations

  • P. M. Farr
  • C. M. Lawrence
  • S. Shuster

There are no affiliations available

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