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Three Generations of Retinoids: Basic Pharmacologic Data, Mode of Action, and Effect on Keratinocyte Proliferation and Differentiation

  • Chapter
Pharmacology of the Skin II

Part of the book series: Handbook of Experimental Pharmacology ((HEP,volume 87 / 2))

Abstract

In the first half of this century, vitamin A and its natural derivatives: retinol, retinal (vitamin A aldehyde), and vitamin A acid, were recognized as playing an essential role in general growth, in the regulation of proliferation and differentiation of epithelial and non-epithelial tissues, in visual processes, and in the capacity of vertebrates to propagate (Wolbach and Howe 1925, 1933).

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Authors
  1. R. Stadler
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Editors and Affiliations

  1. The Institute of Dermatology, St. Thomas’s Hospital, Lambeth Palace Road, SE1 7EH, London, Great Britain

    Malcolm W. Greaves M.D., Ph.D., F.R.C.P.

  2. Department of Dermatology, The Royal Victoria Infirmary, The University of Newcastle upon Tyne, NE1 4LP, Newcastle upon Tyne, Great Britain

    Sam Shuster M.D., Ph. D., F.R.C.P.

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© 1989 Springer-Verlag Berlin Heidelberg

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Stadler, R. (1989). Three Generations of Retinoids: Basic Pharmacologic Data, Mode of Action, and Effect on Keratinocyte Proliferation and Differentiation. In: Greaves, M.W., Shuster, S. (eds) Pharmacology of the Skin II. Handbook of Experimental Pharmacology, vol 87 / 2. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-74054-1_25

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  • DOI: https://doi.org/10.1007/978-3-642-74054-1_25

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