Abstract
The purpose of this chapter is to present five preliminary studies, each of which addresses in one way or another two related issues: 1) the prevalence in mental patients of subclinical hypothyroidism (SC-HO) and a presumably related condition, autoimmune thyroiditis; 2) the relationship between SC-HO (or similar changes) and the response of depressed patients to treatments. None of the studies is definitive. The value of their presentation, each in juxtaposition to the others, is that together they suggest relatively new approaches to the study of the role of thyroid state in mental illness. Through new technology and new conceptualization the solution of this problem may be advanced.
This research was supported by NIMH Clinical Research Center Grant MH-33127 and by NIMH Career Scientist Award (to A.J.P.) MH-22536.
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Prange, A.J., Haggerty, J.J., Browne, J.L., Rice, J.D. (1990). Marginal Hypothyroidism in Mental Illness: Preliminary Assessments of Prevalence and Significance. In: Bunney, W.E., Hippius, H., Laakmann, G., Schmauss, M. (eds) Neuropsychopharmacology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-74034-3_35
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