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Pulmonale Manifestationen

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Bildgebende Diagnostik bei AIDS

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Zusammenfassung

Bereits in den Jahren 1984 und 1985 wurde in den Vereinigten Staaten eine Häufigkeit von 40–50% pulmonaler Erkrankungen bei Patienten mit manifestem erworbenem Immunmangelsyndrom nachgewiesen [6, 28, 30, 66]. Eine Untersuchung des National Heart, Lung and Blood Institute anläßlich eines Workshops 1984 [44] konnte nachweisen, daß bei 1067 Patienten mit manifestem AIDS aus New York, Los Angeles und San Francisco in 441 Fällen (41%) pulmonale Komplikationen vorlagen. Die erkrankten Patienten hatten mindestens eine opportunistische, ungewöhnliche, i. d. R. vital gefährdende pulmonale Infektion. Die bei weitem häufigste Lungenerkrankung wurde durch eine Infektion mit Pneumocystis carinii ausgelöst. Dieser Keim wurde bei 85% der Patienten mit pulmonaler AIDS-Manifestation nachgewiesen. Bei Untersuchungen des Center for Disease Control (CDC) wurde nur in 58% der Patienten mit AIDS eine Pneumocystis-carinii-Pneumonie entweder isoliert oder in Kombination mit einem Kaposi-Sarkom der Lunge gesehen. Die isolierte Lungenmanifestation eines Kaposi-Sarkoms ohne begleitende opportunistische Infektion wird in verschiedenen Arbeiten mit einer Häufigkeit von 8–35% angegeben [28, 29, 44].

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Literatur

  1. Albelda SM, Kern JA, Marinelli DL, Millet WT (1985) Expanding spectrum of pulmonary disease caused by nontuberculous mycobacteria. Radiology 157: 289–296

    PubMed  CAS  Google Scholar 

  2. Bergmann L, Helm E, Nerger K, Schneider M, Tuengerthal S, Meier-Sydow J (1983) Pneumocystis-carinii-Pneumonie bei homosexuellen Männern mit AIDS. Prax Klin Pneumol 37: 1035–1038

    PubMed  Google Scholar 

  3. Broaddus C, Dake M, Steelberg M, Blumenfeld M, Hadley K, Golden J, Hopewell P (1985) Bronchoalveolar lavage and transbronchial biopsy for the diagnosis of pulmonary infections in the acquired immunodeficiency syndrome. Ann Intern Med 102: 747–752

    PubMed  CAS  Google Scholar 

  4. Brown R, Huberman R, Vanley G (1982) Pulmonary features of Kaposi sarcoma. AJR 139: 659–660

    PubMed  CAS  Google Scholar 

  5. Centers for Disease Control: Morbidity and Mortality Weekly Report. (1981) Vol. 30, 21:250–251; (1982) Vol. 31, 23:305–307, Vol. 31, 26:353–361, Vol. 31, 27:265–367, Vol. 31, 37:507–514; (1983) Vol. 31, 30:389–391; (1984) Vol. 32, 52:688–691, Vol. 33, 6:65–67; (1985) Vol. 34, 18: 246–248

    Google Scholar 

  6. Cohen BA, Pomeranz S, Rabinowitz JG, Rosen MJ, Train JS, Norton KJ, Mendelson DS (1984) Pulmonary complications of AIDS: Radiologic features. AJR 143: 115–122

    PubMed  CAS  Google Scholar 

  7. Cox FH, Helwig EB (1959) Kaposi’s sarcoma. Cancer 12: 289–298

    Article  PubMed  CAS  Google Scholar 

  8. Curran J (1985) The epidemiology and prevention of the acquired immunodeficiency syndrome. Ann Intern Med 103: 657–662

    PubMed  CAS  Google Scholar 

  9. Danzig PJ, Richardson D, Rayhanzadeh S, Mauro J, Shoss R (1974) Thoracic involvement of non-African Kaposi’s sarcoma. Chest 66: 522–525

    Article  Google Scholar 

  10. Davis K, Horsburgh C, Hasibas U, Schockert A, Kirkpatrick C (1983) Acquired immunodeficiency syndrome in patients with haemophilia. Ann Intern Med 3: 284–286

    Google Scholar 

  11. Degenhardt S, Ollenschläger G, Ostmeier H (1986) Pulmonale Komplikationen bei AIDS. AIDS-Bericht 2: 96–102

    Google Scholar 

  12. Doppman JL, Gellhoed GW, Vita VTD (1975) Atypical radiographic features in pneumocystis carinii pneumonia. Radiology 114: 39–44

    PubMed  CAS  Google Scholar 

  13. Elliot J, Hoppes W, Platt M, Thomas J, Patel I, Gansar A (1983) The acquired immunodeficiency syndrome and mycobacterium avium-intracellulare bacteremia in a patient with hemophilia. Ann Intern Med 98: 290–293

    Google Scholar 

  14. Fauci A, Macher A, Lango D, Lane H, Rook A, Masur H, Gelmann E (1984) Acquired immunodeficiency syndrome: epidemiologic, clinical, immunologic and therapeutic considerations. Ann Intern Med 100: 92–106

    PubMed  CAS  Google Scholar 

  15. Feinberg SB, Lester RG, Burke AB (1969) The roentgen findings in pneumocystis carinii pneumonia. Radiology 76: 594–599

    Google Scholar 

  16. Fraser RG, Parè JP (1978) Diagnosis of the chest, 2nd edn, Vol. II. Saunders, Philadelphia London Toronto, pp 856–860

    Google Scholar 

  17. Friedmann-Klein AE, Laubenstein LJ, Rubinstein P (1982) Disseminated Kaposi’s sarcoma in homosexual men. Ann Intern Med 96: 693–700

    Google Scholar 

  18. Gamsu G, Hecht ST, Birnberg FA, Coleman DL, Golden JA (1982) Pneumocystis carinii pneumonia in homosexual men. AJR 139: 1037–1041

    Google Scholar 

  19. Gamsu G, Hecht S, Birnberg F, Coleman D, Golden J (1982) Pneumocystis carinii pneumonia in homosexual men. AJR 139: 647–651

    PubMed  CAS  Google Scholar 

  20. Goebel F (1986) Prognostische Faktoren und Verlauf der pneumocystis-cariniiPneumonie. In: AIDS II. Zuckenschwerdt, München Berlin Wien, S 103–106

    Google Scholar 

  21. Goetz O (1958) Über das Antigen der interstitiellen Pneumonie. Klin Wochenschr 36 /3: 118–120

    Article  PubMed  CAS  Google Scholar 

  22. Gottlieb M, Groopman J, Weinstein W, Fahey J, Detels R (1983) The acquired immunodeficiency syndrome. Ann Intern Med 99: 208–220

    PubMed  CAS  Google Scholar 

  23. Gottlieb M, Schroff R, Schanker H, Weisman J, Fan P, Wolf R, Saxon A (1981) Pneumocystis carinii pneumonia and mucosal candidiasis in previous healthy homosexual men. N Engl J Med 305 /24: 1425–1431

    Article  PubMed  CAS  Google Scholar 

  24. Greene JB, Sidhu GS, Lewin S (1982) Mycobacterium-avium-intracellulare: a cause of disseminated life-threatening infection in homosexuals and drug abusers. Ann Intern Med 96: 539–546

    Google Scholar 

  25. Hayerkos H (1984) Assessment of therapy of pneumocystis carinii pneumonia. Am J Med 76: 501–508

    Article  Google Scholar 

  26. Helm EB, Bergmann L, Nerger K (1982) Pneumocystis carinii Pneumonie bei homosexuellen Männern. Dtsch Med Wochenschr 107: 1779–1780

    Google Scholar 

  27. Helm E, Bergmann L, Elert M, Kurth R, Mitrou P, Shah P, Stille W (1983) Erworbenes Immundefekt-Syndrom (AIDS) bei männlichen Homosexuellen in Frankfurt am Main. MMW 125: 1129–1134

    CAS  Google Scholar 

  28. Heron CW, Hine LA, Pozniak AL, Swinburn CR, Johnson NM (1985) Radiologic features in patients with pulmonary manifestations of the acquired immune deficiency syndrome. Clin. Radiol. 36 /6: 583–588

    Article  PubMed  CAS  Google Scholar 

  29. Hill CA, Harle TS, Mansell PW (1983) The prodrome Kaposi sarcoma and infections associated with acquired immunodeficiency syndrome: radiologic findings in 39 patients. Radiology 149: 393–399

    PubMed  CAS  Google Scholar 

  30. Hopewell P, Luce JM (1985) Pulmonary involvement in the acquired immunodeficiency syndrome. Chest 87 /1: 104–112

    Article  PubMed  CAS  Google Scholar 

  31. Hughes W (1984) Five year absence of pneumocystis carinii pneumonitis in a pediatric oncology center. J Infect Dis 150: 305–306

    Article  PubMed  CAS  Google Scholar 

  32. Hymes KB, Cheung T, Greene JB (1981) Kaposi’s sarcoma in homosexual men: a report of eight cases. Lancet 2: 598–600

    Article  PubMed  CAS  Google Scholar 

  33. Jaffe H, Bregman D, Selik R (1983) Acquired immune deficiency syndrome in the United States: the first 1 000 cases. J Infect Dis 148: 339–345

    Article  PubMed  CAS  Google Scholar 

  34. Jaffe H, Hardy A, Morgan W, Darrow W (1985) The acquired immunodeficiency syndrome in gay men. Ann Intern Med 103: 662–664

    PubMed  CAS  Google Scholar 

  35. Kovacs J, Hiemenz J, Marcher A et al. (1984) Pneumocystis carinii pneumonia: a comparison between patients with the acquired immunodeficiency syndrome and patients with other immunodeficiencies. Ann Intern Med 100: 663–671

    PubMed  CAS  Google Scholar 

  36. Leibowitz MR, Dagliotti M, Smith E, Jurray TF (1980) Rapid fatal lymphangioma like Kaposi’s sarcoma. Histopathology 4: 559–566

    Article  PubMed  CAS  Google Scholar 

  37. Lorenzo LJ de, Huang CT, Stone DJ (1986) Roentgenographic patterns of pneumocystis carinii pneumonia in 104 patients with AIDS. Chest 19 /3: 323–327

    Google Scholar 

  38. Loring WE, Wolman SR (1965) Idiopathic multiple haemorrhagic sarcoma of lung (Kaposi’s sarcoma). NY State J Med 65: 668–676

    CAS  Google Scholar 

  39. Mann SG (1974) Kaposi’s sarcoma. AJR 121: 793–799

    CAS  Google Scholar 

  40. Masur H, Michelis M, Greene J et al (1981) An outbreak of community acquired pneumocystis carinii pneumonia. N Engl J Med 305 /24: 1431–1438

    Article  PubMed  CAS  Google Scholar 

  41. Marinelli D, Albelda S, Williams T, Kern J, Jozzo R, Mitter W (1986) Nontuberculous mycobacterial infection in AIDS: clinical, pathologic, and radiographic features. Radiology 160: 77–82

    PubMed  CAS  Google Scholar 

  42. McCauley DI, Naidich DP, Leitman BS, Reede DL, Laubenstein L (1982) Radiographic patterns of opportunistic lung infections and Kaposi sarcoma in homosexual men. AJR 139: 653–658

    PubMed  CAS  Google Scholar 

  43. Meuwissen J, Leeuwenberg A, Beckers P, Sieben M (1977) Parasitologic and serologic observations of infections with pneumocystis in humans. J Infect Dis 136: 43–49

    Article  PubMed  CAS  Google Scholar 

  44. Murray JF, Felton Cp, Garay SM (1984) Pulmonary complications of the acquired immunodeficiency syndrome: report of a National Heart, Lung and Blood Institute Workshop. N Engl J Med 310: 1682–1684

    Article  PubMed  CAS  Google Scholar 

  45. Naidich DP, Garay SM, Leitman BS, McCauley DJ (1987) Radiographic manifestations of pulmonary disease in the acquired immunodeficiency syndrome. Sem Roentgenol 22 /1: 14–30

    Article  CAS  Google Scholar 

  46. Nesbitt S, Mark PF, Zimmermann HM (1985) Disseminated visceral idiopathic haemorrhagic sarcoma (Kaposi’s disease): report of case with necropsy findings. Ann Intern Med 22: 601–605

    Google Scholar 

  47. Ognibene F, Shelhamer J, Gill Vet al. (1984) The diagnosis of pneumocystis carinii pneumonia in patients with the acquired immunodeficiency syndrome using subsegmental bronchoalveolar lavage. Am Rev Respir Dis 129: 929–932

    PubMed  CAS  Google Scholar 

  48. Ognibene F, Steis R, Macher A et al. (1985) Kaposi’s sarcoma causing pulmonary infiltrates and respiratory failure in the acquired immunodeficiency syndrome. Ann Intern Med 102: 471–475

    PubMed  CAS  Google Scholar 

  49. Pitchenik A, Russel B, Cleary T, Pejovic I, Cole C, Snider D (1982)The prevalence of tuberculosis and drug resistance among Haitians. N Engl J Med 307/3:162–165

    Article  Google Scholar 

  50. Pitchenik A, Fischl M (1983) Disseminated tuberculosis and the acquired immunodeficiency syndrome. Ann Intern Med 97: 112

    Google Scholar 

  51. Pitchenik A, Fischt M, Dickinson G et al. (1983) Opportunistic infections and Kaposi’s sarcoma among Haitians: evidence of a new acquired immunodeficiency state. Ann Intern Med 98: 277–284

    PubMed  CAS  Google Scholar 

  52. Pitchenik A, Rubinson H (1985) The radiographic appearance of tuberculosis in patients with the acquired immune deficiency syndrome (AIDS) and pre AIDS. Am Rev Respir Dis 131: 393–396

    PubMed  CAS  Google Scholar 

  53. Ramaswamy G, Jagadha V, Tchertkoff V (1985) Diffuse alveolar damage and interstitial fibrosis in acquired immunodeficiency syndrome patients without current pulmonary infection. Arch Path Lab Med 109: 408–412

    PubMed  CAS  Google Scholar 

  54. Reichert C, O’Leary T, Levens D, Simrell C, Macher A (1983) Autopsy pathology in the acquired immunodeficiency syndrome. Am J Pathol 112: 357–382

    PubMed  CAS  Google Scholar 

  55. Rosenzweig D (1979) Pulmonary mycobacterial infections due to mycobacterium intracellulare-avium complex. Chest 75: 115–119

    Article  PubMed  CAS  Google Scholar 

  56. Schmidts H, Schneider M, Müller H, Prosek H, Hübner K (1985) Morphologische Befunde bei erworbenem Immundefekt-Syndrom (AIDS). In: Helm EB, Stille W (Hrsg) AIDS: Acquired immune deficiency syndrome. Zuckenschwerdt, München Berlin Wien, S 42–57

    Google Scholar 

  57. Shah P (1982) Pneumocystis-carinii-Pneumonie bei homosexuellen Männern. DMW 107: 1779–1780

    Google Scholar 

  58. Shelhamer J, Ognibene F, Marcher A et al. (1984) Persistence of pneumocystis carinii in lung tissue of acquired immunodeficiency syndrome patients treated for pneumocystis pneumonia. Am Rev Respir Dis 130: 1161–1165

    PubMed  CAS  Google Scholar 

  59. Simmons J, Suffredini A, Lack E et al. (1987) Nonspecific interstitial pneumonitis in patients with AIDS: radiologie features. AJR 149: 265–268

    PubMed  CAS  Google Scholar 

  60. Singer C, Armstrong D, Rosen P, Walzer P, Yu B (1979) Diffuse pulmonary infiltrates in immunosuppressed patients. Am J Med 66: 110–120

    Article  PubMed  CAS  Google Scholar 

  61. Stark P, Nguyen M (1984) Pneumocystis-Pneumonie als Ausdruck eines erworbenen Immunmangels bei homosexuellen Männern (AIDS). Prax Klin Pneumol 38: 26–28

    PubMed  CAS  Google Scholar 

  62. Stern R, Gamsu G, Golden J, Hirji M, Webb W, Abrams D (1984) Intrathoracic adenopathy: differential feature of AIDS and diffuse lymphodenopathy syndrome. AJR 142: 689–692

    PubMed  CAS  Google Scholar 

  63. Stoyer D, White D, Romano P, Gellene R, Robeson W (1985) Spectrum of pulmonary diseases associated with the acquired immune deficiency syndrome. Am J Med 78: 429–437

    Article  Google Scholar 

  64. Sufferidini A, Ognibene F, Lack E et al. (1987) Nonspecific interstitial pneumocystis: A common cause of pulmonary disease in the acquired immunodeficiency syndrome. Ann Intern Med 107: 7–13

    Google Scholar 

  65. Sunderam G, Maniatis T, Kapila R, Donald R, Reichman LB (1984) Mycobacterium tuberculosis disease with unusual manifestations is relatively common in acquired immunodeficiency syndrome (AIDS) Am Rev Resp Dis 129 (Suppl): 191

    Google Scholar 

  66. Suster B, Akerman M, Orenstein M, Wax MR (1986) Pulmonary manifestations of AIDS. Review of 106 episodes. Radiology 161: 87–93

    PubMed  CAS  Google Scholar 

  67. Szabados A, Schiers G, Deinhardt F (1985) Die Pneumozystis carinii Pneumonie. Internist 26: 335–340

    PubMed  CAS  Google Scholar 

  68. Thomson HK, Jacobsen M, Malochow-Maler A (1981) Kaposi’s sarcoma among homosexual men in Europe. Lancet 2: 688

    Article  Google Scholar 

  69. Tuengerthal S, Helm E, Staszewski S, Schmidts E (1985) Röntgenthoraxbefunde der Pneumocystis-carinii-Pneumonie bei AIDS. In: Helm EB, Stille W (Hrsg) AIDS: Acquired immune deficiency syndrome. Zuckenschwerdt, München Berlin Wien, S 93–102

    Google Scholar 

  70. Turbiner E, Yen S, Rosen P, Bains M, Benua R (1978) Abnormal gallium scintigraphy in pneumocystis carinii pneumonia with a normal chest radiograph. Radiology 127: 437–438

    PubMed  CAS  Google Scholar 

  71. Vanley G, Huberman R, Lufkin R (1982) Atypical pneumocystis carinii pneumonia in homosexual men with unusual immunodeficiency. AJR 138: 1037–1041

    PubMed  CAS  Google Scholar 

  72. Vetter N (1983) Die Lungentuberkulose beim erworbenen Immundefektsyndrom (AIDS). Prax Klin Pneumol 39: 754–756

    Google Scholar 

  73. Vireira J, Frank E, Spira T, Landesman SH (1983) Acquired immune deficiency in Haitians. N Engl J Med 308 /3: 125–129

    Article  Google Scholar 

  74. Wallace JM, Hannah J (1985) Mycobacterium avium-intracellulare infection found at autopsy in patients with the acquired immunodeficiency syndrome (AIDS). Am Rev Respir Dis 131: 224

    Google Scholar 

  75. Weiske R, Buck J, Schneider R, Hannemann T, Krauss B (1986) Lungenkomplikationen bei AIDS. Radiologe 26: 3–9

    PubMed  CAS  Google Scholar 

  76. Woolfenden J, Carrasquillo J, Larson S et al (1987) Acquired immunodeficiency syndrome, Ga-67 citrate imaging. Radiology 162: 383–387

    PubMed  CAS  Google Scholar 

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Langer, M. (1989). Pulmonale Manifestationen. In: Bildgebende Diagnostik bei AIDS. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-74023-7_3

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  • DOI: https://doi.org/10.1007/978-3-642-74023-7_3

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