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Peptide Siderophores from Pseudomonas

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Natural Products Chemistry III

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Abstract

A sufficient supply of Fe ions is essential for all living organisms. But although iron is amongst the most abundant elements making up about 3.5% of the earth crust it is hard to come by for microorganisms. In the original (reducing) atmosphere of the world iron existed in its divalent form and was thus sufficiently soluble, but when the atmosphere became oxidative due to the photosynthetic activity of certain procarionts iron was precipitated as polymeric ferric oxide hydrate. The consequence is that at the physiological pH of 7.4 [Fe3+]max is 8.9. 10-7 g/1, by far too low for survival (the optimum for microorganisms is about 5.10-6 g/1). Therefore, microroganisms did develop intricate chemical systems to make iron available for them. This is achieved by creating a reductive microbiotope or - more commonly - by giving off complexing agents (ref. 1).

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Authors and Affiliations

  1. Institut für Organische Chemie der Universität zu Köln, Greinstr. 4, D-5000, Köln 41, West Germany

    Prof. Dr. Herbert Budzikiewicz

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  1. Prof. Dr. Herbert Budzikiewicz
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Editors and Affiliations

  1. HEJ Research Institute of Chemistry, University of Karachi, Karachi-32, Pakistan

    Atta-ur-Rahman

  2. Department of Chemistry, Northeastern University, 360 Huntington Avenue, Boston, MA, 02115, USA

    Philip William Le Quesne

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© 1988 Springer-Verlag Berlin Heidelberg

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Budzikiewicz, H. (1988). Peptide Siderophores from Pseudomonas . In: Atta-ur-Rahman, Le Quesne, P.W. (eds) Natural Products Chemistry III. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-74017-6_18

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  • DOI: https://doi.org/10.1007/978-3-642-74017-6_18

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-74019-0

  • Online ISBN: 978-3-642-74017-6

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