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Isoquinoline Alkaloid Synthesis via Arynes

  • Conference paper
Natural Products Chemistry III

Abstract

A number of aporphine alkaloids have been isolated in this laboratory in such small quantities that their structure could at first only be stablished on the basis of their spectroscopic characteristics (Ref. 1). The need to confirm the structures of these new alkaloids and to obtain them in quantities sufficient to allow investigation of their pharmacological properties led us to attempt their synthesis by classical methods, but the problems encountered in some cases forced us to try modified or radically different approaches. As a result, we have developed a new synthetic procedure that is applicable to a variety of different kinds of isoquinoline alkaloids.

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Author information

Authors and Affiliations

  1. Department of Organic Chemistry, University of Santiago, 15706, Santiago de Compostela, Spain

    L. Castedo & E. Guitián

Authors
  1. L. Castedo
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  2. E. Guitián
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Editor information

Editors and Affiliations

  1. HEJ Research Institute of Chemistry, University of Karachi, Karachi-32, Pakistan

    Atta-ur-Rahman

  2. Department of Chemistry, Northeastern University, 360 Huntington Avenue, Boston, MA, 02115, USA

    Philip William Le Quesne

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© 1988 Springer-Verlag Berlin Heidelberg

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Castedo, L., Guitián, E. (1988). Isoquinoline Alkaloid Synthesis via Arynes. In: Atta-ur-Rahman, Le Quesne, P.W. (eds) Natural Products Chemistry III. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-74017-6_12

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  • DOI: https://doi.org/10.1007/978-3-642-74017-6_12

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-74019-0

  • Online ISBN: 978-3-642-74017-6

  • eBook Packages: Springer Book Archive

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