Hormonally Related Non-Neoplastic Conditions of the Ovary

  • H.-E. Stegner
Part of the Current Topics in Pathology book series (CT PATHOLOGY, volume 78)


There are few pathological alterations of the ovary that do not in some way influence the hormonal homeostasis either by directly affecting the compartment of steroid secreting cells or by interacting with gonadotropic hormones or ovarian steroids at various levels of the regulatory axis. Owing to their origin from a common blastema, most ovarian cells are capable of steroid biosynthesis, but there is a changing pattern of ovarian steroidogenesis and of response to gonadotropic stimulation during the different periods of female life. Similar pathogenetic stimuli may lead to different responses depending on the age and the actual structural condition of the gonads. Some of these hormonally related conditions are discussed in this chapter. Unlike true neoplasms and other pathological conditions of the ovary, there exists no clear classification of hormonally related, non-neoplastic ovarian disease. A broad spectrum of conditions with different pathogenesis and morphology will be considered in this chapter.


Obstet Gynecol Corpus Luteum Clomiphene Citrate Primordial Follicle Premature Ovarian Failure 
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