Cerebral Hemodynamics in Benign Intracranial Hypertension Studied with PET
The pathogenesis of benign intracranial hypertension (BIH) remains poorly understood. Many investigators suspect the disorder to be caused by obstruction of CSF outflow at the arachnoid villi (Johnston 1973), but this same mechanism is also suspected to cause an entirely different syndrome, normal pressure hydrocephalus. In 1985, I proposed that BIH might be caused be weakness in the walls of the dural venous sinuses, resulting in compression of the venous sinuses, partial venous outflow obstruction, and elevated ICP (Junck 1986).
KeywordsCerebral Blood Flow Lumbar Puncture Cerebral Perfusion Pressure Cerebral Blood Volume Venous Sinus
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- Junck L (1986) Benign intracranial hypertension and normal pressure hydrocephalus: Theoretical conditions. In: Miller JD, Teasdale GM, Rowan JO, Galbraith SL, Mendelow AD (eds) Intracranial pressure VI. Springer, Berlin Heidelberg New York Tokyo, pp 447–450Google Scholar